FDA approves alectinib as adjuvant treatment for ALK-positive non-small cell lung cancer
FDA Approves Genentech's Alecensa as First Adjuvant Treatment for People With ALK-Positive Early-Stage Lung Cancer
Moving drugs into early-stage cancers is in vogue these days. Roche has just posted a trial win for its targeted lung cancer therapy Alecensa that should enable earlier use, while eliciting a sense of déjà vu from a study of AstraZeneca’s Tagrisso.
Genentech’s Alecensa Reduces the Risk of Disease Recurrence or Death by an Unprecedented 76% in People With ALK-Positive Early-Stage Non-Small Cell Lung Cancer
Roche on Friday said one of its medicines succeeded in a Phase 3 trial of people whose lung tumors were driven by a well-known cancer gene, positioning its therapy to become the first available in that specific setting.
Adjuvant treatment with alectinib (Alecensa) generated a statistically significant and clinically meaningful improvement in disease-free survival (DFS) compared with platinum-based chemotherapy in patients with completely resected stage IB to IIIA, ALK-positive non–small cell lung cancer (NSCLC), meeting the primary end point of the phase 3 ALINA trial (NCT03456076).1
Roche made a splash at the American Society of Clinical Oncology (ASCO) annual meeting three years ago with data showing that its Alecensa could top Pfizer’s Xalkori at keeping ALK-positive lung-cancer at bay. This time, it’s back with long-term data showing it can best Xalkori at keeping patients alive, too.
The National Institute for Health and Care Excellence (NICE) has published guidance recommending the use of Pfizer's Lorviqua (lorlatinib) for a certain form of lung cancer on the NHS.
Basel, 7 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that new data from clinical trials of 19 approved and investigational medicines across 21 cancer types, will be presented at the ASCO20 Virtual Scientific Program organised by the American Society of Clinical Oncology (ASCO), which will be held 29-31 May, 2020. A total of 120 abstracts that include a Roche medicine will be presented at this year's meeting.
FDA Confirms Paragraph IV Patent Challenge of Alecensa 208434 (Alectinib 150 mg)Capsules