CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, announced that it has entered into a global strategic license with NantCell, Inc., for the exclusive rights to develop and commercialize aldoxorubicin for all indications. NantCell, a private subsidiary of NantWorks, LLC, is a clinical stage immuno-oncology company focused on developing novel molecularly targeted therapeutics including antibody, T-cell and NK cell based treatments for patients with cancer.
Controversial billionaire biotech entrepreneur Patrick Soon-Shiong and one of his I-O outfits NantCell has paid $13 million up front, with $356 million in biobucks on the table, to license CytRx’s orphan cancer drug aldoxorubicin.
CytRx Corporation CYTR announced that the it has reached an agreement with the regarding the path to filing for its new drug application (NDA) for its lead candidate aldoxorubicin being developed for the treatment of soft tissue sarcomas (STS)
BRIEF-Cytrx says FDA agreement on regulatory pathway for Aldoxorubicin
On Tuesday, CytRx said updated data testing aldoxorubicin against investigator's choice of treatment demonstrated a statistically significant improvement in progression-free survival (PFS) between in 246 patients with leiomyosarcoma and liposarcoma. The trial included a total of 433 patients. Leiomyosarcoma and liposarcoma are the two most common types of STS and accounted for 57 percent of the patients enrolled in the trial, CytRx said in a statement.