Affinia Therapeutics, an innovative gene therapy company with a proprietary platform for rationally-designed adeno-associated virus (AAV) vectors and ...
The MA-based preclinical gene therapy biotech, which got $60 million in startup capital from New Enterprise Associates, F-Prime and Atlas in 2019, filed an S-1 with the SEC on Tuesday, announcing initial plans to go public and penciling in a $100 million raise. Affinia plans to list under the ticker $AFTX.
WALTHAM, Mass., Dec. 14, 2021 (GLOBE NEWSWIRE) -- Affinia Therapeutics, an innovative gene therapy company with a proprietary platform for rationally-designed adeno-associated virus (AAV) gene therapies for rare and prevalent devastating diseases, today announced the appointment of Thomas (Tommy) Leggett as Chief Financial Officer (CFO).
WALTHAM, Mass., Oct. 06, 2021 (GLOBE NEWSWIRE) -- Affinia Therapeutics, an innovative gene therapy company with a proprietary platform for rationally-designed adeno-associated virus (AAV) gene therapies for rare and prevalent devastating diseases, today announced the appointment of Carole Faig to the Affinia Therapeutics Board of Directors.
WALTHAM, Mass., Sept. 08, 2021 (GLOBE NEWSWIRE) -- Affinia Therapeutics, an innovative gene therapy company with a proprietary platform for rationally-designed adeno-associated virus (AAV) capsids developing gene therapies for rare and prevalent devastating diseases, today announced the first two indications it will pursue with its next-generation gene therapies: metachromatic leukodystrophy (MLD), a rare, progressive, and fatal neurodegenerative disease, and brain metastases secondary to human epidermal growth factor receptor 2 positive (HER2+) breast cancer (BMBC), a common and deadly form of cancer. The company’s therapeutic candidates for these two indications are directed at targets in the central nervous system (CNS) and are based on its proprietary capsid, Anc80L65, which when delivered intrathecally has been observed to be 40-times more efficient at delivering genetic payloads to regions of the brain than AAV9, a capsid used by others in the field for CNS-directed gene therapies.
Data shows multiple vectors with superiority to AAV9 in CNS, systemic approaches to target muscle while detargeting liver, and improvements in manufacturability
Affinia Therapeutics, a Waltham-based biotech working on gene therapies to treat diseases using technology developed at Massachusetts Eye and Ear, said Monday it has raised $110 million in a new venture capital round.
Affinia Therapeutics, a biotech developing adeno-associated virus vectors and gene therapies, has raked in $110 million through a series B financing to move its programs into the clinic.
WALTHAM, Mass., March 31, 2020 (GLOBE NEWSWIRE) -- Affinia Therapeutics, an innovative gene therapy company with a platform for rationally designed adeno-associated virus (AAV) vectors and gene therapies and a mission to develop transformative medicines for devastating diseases, today announced it has closed an oversubscribed $60 million Series A financing. Seed venture investors F-Prime Capital and New Enterprise Associates (NEA) co-led the round alongside new investor Atlas Venture, with participation from seed investors Alexandria Venture Investments, Lonza and Partners Innovation Fund.