Johnson & Johnson Announces Expansion of IMBRUVICA (ibrutinib) Label in the U.S.
An Imbruvica combo regimen could have a new future in MCL
Additional data from the Phase 2 CAPTIVATE study, show 82 percent of patients with previously untreated chronic lymphocytic leukaemia (CLL) treated with fixed-duration ibrutinib plus venetoclax did...
AbbVie recently filed a patent infringement lawsuit against BeiGene over their blockbuster BTK franchises. Although the litigation was launched right after a patent’s issuance, AbbVie may actually have a case here, according to one expert.
The addition of ibrutinib (Imbruvica) to bendamustine plus rituximab (Rituxan; BR) or R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) did not lead to a statistically significant improvement in progression-free survival (PFS) vs either chemoimmunotherapy regimen alone in patients with relapsed/refractory follicular lymphoma or marginal zone lymphoma (MZL), according to findings from the phase 3 SELENE trial (NCT01974440) presented at the 17th Annual International Conference on Malignant Lymphoma.1
The combination of ibrutinib (Imbruvica), obinutuzumab (Gazyva), and venetoclax (Venclexta) was associated with prolonged survival in patients with newly diagnosed or relapsed/refractory mantle cell lymphoma (MCL), according to long-term follow-up data from the phase 1/2 OAsIs trial (NCT02558816) presented at the 2023 EHA Congress.1
Dazzling trial data, followed by FDA approval three months ago in the most common form of leukemia have set BeiGene’s Brukinsa up to become the dominant force in treating blood cancer.
High Wycombe, 21 April 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson is pleased to announce that the National Institute for Health and Care Excellence (NICE) has recommended Imbruvica® (ibrutinib) plus venetoclax as an option for untreated chronic lymphocytic leukaemia (CLL) in adults.[1]
NORTH CHICAGO, Ill., April 6, 2023 – AbbVie (NYSE: ABBV) announced today the intent to voluntarily withdraw, in the U.S., accelerated IMBRUVICA® (ibrutinib) approvals for patients with the blood cancers mantle cell lymphoma (MCL) who have received at least one prior therapy and with marginal zone lymphoma (MZL) who require systemic therapy and have received at least one prior anti-CD20-based therapy.
NEW YORK/WASHINGTON, March 13 (Reuters) - The blood thinner Eliquis from Bristol Myers Squibb, Pfizer's breast cancer drug Ibrance and AbbVie's leukemia treatment Imbruvica are likely to be among 10 big-selling medicines subject to U.S. price negotiations for 2026, according to five Wall Street and academic analyses shared with Reuters.