
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : YOLT-101
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : AstraZeneca-CICC healthcare investment fund
Deal Size : $45.0 million
Deal Type : Series B Financing
YolTech Therapeutics Raises $45 Million in Series B Financing Led by AstraZeneca-CICC
Details : The financing aims to advance the clinical development of YOLT-101, which is being evaluated for the treatment of Familial Hypercholesterolemia.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
September 11, 2025
Lead Product(s) : YOLT-101
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : AstraZeneca-CICC healthcare investment fund
Deal Size : $45.0 million
Deal Type : Series B Financing

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Lead Product(s) : YOLT-101
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
YolTech Shares Initial Data On YOLT-101 In-Vivo Base Editing for Cholesterol
Details : YOLT-101 is a next-generation in vivo base-editing therapeutic, being evaluating in the early-stage clinical trial studies for the treatment of Familial Hypercholesterolemia.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
April 28, 2025
Lead Product(s) : YOLT-101
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : YOLT-203
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Northwestern University
Deal Size : Inapplicable
Deal Type : Inapplicable
YolTech Reports Positive Clinical Data for YOLT-203 Gene Therapy in PH1
Details : YOLT-203 is an innovative in vivo gene editing therapy, which is currently being evaluated for the treatment of patients with primary hyperoxaluria type 1 (PH1).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
February 25, 2025
Lead Product(s) : YOLT-203
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Northwestern University
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : YOLT-204
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
YolTech Initiates Trial for YOLT-204, Bone Marrow-Targeted Gene Editing for β-Thalassemia
Details : YOLT-204 is an off-the-shelf in vivo gene editing therapy developed for TDT, it delivers a gene editor to hematopoietic stem cells which helps to induce expression of fetal hemoglobin.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
January 21, 2025
Lead Product(s) : YOLT-204
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : YOLT-201
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
YolTech Therapeutics Announces Successful Dose Escalation in Phase I Trial Of YOLT-201
Details : YOLT-201 Injection is a TTR inhibitor oligonucleotide drug candidate. It is being evaluated for the treatment of Transthyretin Amyloidosis Cardiomyopathy.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
December 21, 2024
Lead Product(s) : YOLT-201
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : YOLT-101
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : SHENZHEN SALUBRIS PHARMACEUTICALS
Deal Size : $145.3 million
Deal Type : Licensing Agreement
YolTech Signs Licensing Deal with Salubris For YOLT-101 in China
Details : YolTech will continue to advance the preclinical development of YOLT-101, while Salubris will be responsible for preparing and conducting clinical trials within the licensed territory.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
August 27, 2024
Lead Product(s) : YOLT-101
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : SHENZHEN SALUBRIS PHARMACEUTICALS
Deal Size : $145.3 million
Deal Type : Licensing Agreement

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Lead Product(s) : YOLT-203
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
YolTech Administers First Dose of Gene Editing Therapy YOLT-203 for PH1
Details : YOLT-203 is an innovative in vivo gene editing therapy, which is currently being evaluated for the treatment of patients with primary hyperoxaluria type 1 (PH1).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
August 22, 2024
Lead Product(s) : YOLT-203
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : YOLT-201
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : YOLT-201 is a Oligonucleotide drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Cardiomyopathy-associated with Amyloidosis, Hereditary, Transthyretin-Related.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
August 06, 2024
Lead Product(s) : YOLT-201
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : YOLT-201
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
First Patient Dosed in Phase I Clinical Trial of YOLT-201
Details : YOLT-201 Injection is a TTR inhibitor oligonucleotide drug candidate. It is being evaluated for the treatment of Transthyretin Amyloidosis Cardiomyopathy.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
July 11, 2024
Lead Product(s) : YOLT-201
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : YOLT-101
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
First Patient Dosed in Clinical Trial of YOLT-101 for the Treatment of FH
Details : YOLT-101, the company's in vivo genome editing candidate being developed as a single dose, potentially curative therapy for the treatment of high-risk heterozygous familial hypercholesterolemia.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
April 02, 2024
Lead Product(s) : YOLT-101
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
