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    [{"orgOrder":0,"company":"Whitehawk Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibiotic","year":"2022","type":"Inapplicable","leadProduct":"Sirolimus","moa":"FK506-binding protein 1A","graph1":"Oncology","graph2":"Phase II","graph3":"Whitehawk Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Whitehawk Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Whitehawk Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Whitehawk Therapeutics","sponsor":"Kaken Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibiotic","year":"2025","type":"Divestment","leadProduct":"Sirolimus","moa":"FK506-binding protein 1A||mTOR","graph1":"Oncology","graph2":"Approved FDF","graph3":"Whitehawk 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    Find Clinical Drug Pipeline Developments & Deals by Whitehawk Therapeutics

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                            01

                            Whitehawk Therapeutics

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                            Whitehawk Therapeutics

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                            Lead Product(s) : Sirolimus Protein-bound Particle,Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : $100.0 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Whitehawk Finalizes Aadi Sale To Kaken In Strategic Transformation

                            Details : Through the divestment, Kaken assumes ownership of FYARRO (sirolimus protein-bound particles for injectable suspension) used to treat adults with malignant perivascular epithelioid cell tumor.

                            Product Name : Fyarro

                            Product Type : Antibiotic

                            Upfront Cash : $100.0 million

                            March 26, 2025

                            Lead Product(s) : Sirolimus Protein-bound Particle,Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : $100.0 million

                            Deal Type : Divestment

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                            02

                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Gemcitabine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : MD Anderson Cancer Center

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tiss...

                            Details : Gemcitabine is a Cytotoxic Drug drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Leiomyosarcoma.

                            Product Name : Undisclosed

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            March 13, 2024

                            Lead Product(s) : Gemcitabine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : MD Anderson Cancer Center

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Whitehawk Therapeutics

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Whitehawk Therapeutics

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                            Lead Product(s) : Sirolimus,Adagrasib,Sotorasib

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aadi Bioscience Announces Improved Anti-Tumor Activity of KRAS Inhibitors in Combination with Nab-sirolimus at...

                            Details : ABI-009 (Nab-sirolimus) is a novel albumin-bound nanoparticle form of the mTOR inhibitor sirolimus and is approved for the treatment of locally advanced unresectable or metastatic malignant perivascular epithelioid cell tumor (PEComa).

                            Product Name : Fyarro

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            October 27, 2022

                            Lead Product(s) : Sirolimus,Adagrasib,Sotorasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Adagrasib,Nab-Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Mirati Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Mirati Therapeutics and Aadi Bioscience Partner to Evaluate the Combination of Adagrasib with Nab-sirolimus in...

                            Details : Under the terms of the collaboration agreement, Mirati will be responsible for sponsoring and operating the Phase 1/2 study of Adagrasib (MRTX849), and jointly with Aadi, will oversee and share the cost of the study.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            October 12, 2022

                            Lead Product(s) : Adagrasib,Nab-Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Mirati Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            05

                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Avoro Capital

                            Deal Size : $72.5 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Aadi Bioscience Announces $72.5 Million Private Placement Equity Financing

                            Details : The company intends to use net proceeds from the financing to fund research and development of Nab-sirolimus and additional clinical opportunities with FYARRO and for working capital and general corporate purposes.

                            Product Name : Fyarro

                            Product Type : Antibiotic

                            Upfront Cash : Undisclosed

                            September 22, 2022

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Avoro Capital

                            Deal Size : $72.5 million

                            Deal Type : Private Placement

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                            06

                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aadi Bioscience Announces Exploratory Biomarker Data from Patients in Its AMPECT Trial and Expanded Access Pro...

                            Details : Nab-sirolimus is an albumin-bound mTOR inhibitor approved by the U.S. Food and Drug Administration (FDA) as FYARRO™ for the treatment of adult patients with locally advanced unresectable or metastatic malignant PEComa.

                            Product Name : Fyarro

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            May 26, 2022

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Whitehawk Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Foundation Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Aadi Bioscience Announces Collaborations with Next Generation Sequencing Leaders

                            Details : Partners will collect and analyze clinical and molecular data to determine which patients may be eligible to participate in Aadi’s PRECISION 1 clinical trial for ABI-009. The goals are to increase patient match rate, reduce screen failure rate and incr...

                            Product Name : Fyarro

                            Product Type : Antibiotic

                            Upfront Cash : Undisclosed

                            May 09, 2022

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Foundation Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            Whitehawk Therapeutics

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aadi Bioscience Announces Data Presentation on incidence of TSC1 and TSC2 Alterations in Advanced Cancers at t...

                            Details : Based on data from the AMPECT trial with FYARRO and following discussions with the FDA about other emerging data with FYARRO, Aadi has initiated PRECISION 1, a tumor-agnostic registrational trial in mTOR inhibitor-naïve solid tumors.

                            Product Name : Fyarro

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            April 08, 2022

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Whitehawk Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aadi Bioscience Announces First Patient Dosed in its PRECISION 1 Phase 2 Registrational Trial of nab-Sirolimus...

                            Details : FYARRO is an mTOR inhibitor indicated for the treatment of adult patients with locally advanced unresectable or metastatic malignant perivascular epithelioid cell tumor (PEComa).

                            Product Name : Fyarro

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            March 31, 2022

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Whitehawk Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aadi Bioscience to Present New Preclinical Data on nab-Sirolimus (ABI-009) at AACR-NCI-EORTC Virtual Internati...

                            Details : nab-Sirolimus (ABI-009), an mTOR inhibitor bound to human albumin that has demonstrated significantly higher tumor accumulation, greater mTOR target suppression, and increased tumor growth inhibition over other mTOR inhibitors.

                            Product Name : Fyarro

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            October 06, 2021

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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