
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Lonigutamab
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : VB421 binds to IGF-1R with sub-50 pM potency and possesses favorable biophysical properties that may provide a differentiated product profile relative to other anti-IGF-1R antibodies.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 31, 2022
Lead Product(s) : Lonigutamab
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : VB517
Therapeutic Area : Immunology
Study Phase : IND Enabling
Recipient : Novelty Nobility
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : VB517 is a fully human mAb with low-picomolar affinity for c-KIT and has demonstrated potent suppression of human mast cell activation in preclinical models. ValenzaBio plans to initiate clinical studies of VB517 in 2023.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
February 15, 2022
Lead Product(s) : VB517
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Recipient : Novelty Nobility
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : CD19-targeting mAb
Therapeutic Area : Nephrology
Study Phase : Phase I/ Phase II
Sponsor : Fidelity Management & Research Company
Deal Size : $70.0 million
Deal Type : Series A Financing
Details : The fundraise will support the advancement and expansion of ValenzaBio’s pipeline toward clinical development, including VB119, anti-CD19 monoclonal antibody for the treatment of membranous nephropathy and VB421, an anti-IGF-1R antibody.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
April 08, 2021
Lead Product(s) : CD19-targeting mAb
Therapeutic Area : Nephrology
Highest Development Status : Phase I/ Phase II
Sponsor : Fidelity Management & Research Company
Deal Size : $70.0 million
Deal Type : Series A Financing
