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    [{"orgOrder":0,"company":"Xeris Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Other Large Molecule","year":"2020","type":"Inapplicable","leadProduct":"Pramlintide","moa":"||Amylin receptor AMY1, CALCR\/RAMP1","graph1":"Endocrinology","graph2":"Phase II","graph3":"Xeris Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Xeris Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Xeris Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Adocia","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"FRANCE","productType":"Peptide","year":"2021","type":"Inapplicable","leadProduct":"Insulin Lispro","moa":"||Insulin receptor","graph1":"Endocrinology","graph2":"Phase II","graph3":"Adocia","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Adocia \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Adocia \/ Inapplicable"},{"orgOrder":0,"company":"Adocia","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nutrition and Weight Loss","country":"FRANCE","productType":"Other Large Molecule","year":"2021","type":"Inapplicable","leadProduct":"Pramlintide","moa":"||Amylin receptor AMY1, CALCR\/RAMP1","graph1":"Nutrition and Weight Loss","graph2":"Preclinical","graph3":"Adocia","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Subcutaneous Infusion","sponsorNew":"Adocia \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Adocia \/ Inapplicable"}]

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                            01

                            Adocia

                            France arrow
                            Peptide Process CMC
                            Not Confirmed

                            Adocia

                            France arrow
                            Peptide Process CMC
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                            Lead Product(s) : Insulin Lispro,Pramlintide

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Adocia Initiates BC LisPram Phase 1 Clinical Trial in Pump for People with Type 1 Diabetes

                            Details : Pramlintide, despite being the only drug approved as an adjunct to insulin in type 1 diabetes, is underused as it requires three additional daily injections in addition to the multiple injections of insulin.

                            Product Name : BC LisPram

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            June 29, 2021

                            Lead Product(s) : Insulin Lispro,Pramlintide

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Adocia

                            France arrow
                            Peptide Process CMC
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                            Adocia

                            France arrow
                            Peptide Process CMC
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                            Lead Product(s) : Pramlintide,Exenatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Adocia Expands Clinical Development to Obesity with Patent Applications on Short-Acting Multihormonal Combinat...

                            Details : Three patent families have been filed to cover novel hormonal combinations: pramlintide-exenatide and glucagon-exenatide-both combinations demonstrated promising effects in obesity treatment.

                            Product Name : PramExe

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            May 26, 2021

                            Lead Product(s) : Pramlintide,Exenatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Xeris Pharmaceuticals

                            U.S.A arrow
                            Peptide Process CMC
                            Not Confirmed

                            Xeris Pharmaceuticals

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                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Pramlintide,Insulin

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Xeris Pharmaceuticals Announces Positive Topline Results from the Phase 2 Comparative Study of XP-3924 in Adul...

                            Details : XP-3924 resulted in 62% reduction of hyperglycemia after a glucose challenge. XP-3924 showed promising glucose control when compared to both Humulin R and co-administered injections of Humulin R & Symlin and it showed improved glucose control when compar...

                            Product Name : Xerisol

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            June 18, 2020

                            Lead Product(s) : Pramlintide,Insulin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            AstraZeneca

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                            Peptide Process CMC
                            Not Confirmed

                            AstraZeneca

                            United Kingdom arrow
                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Juvenile Diabetes Research Foundation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Effect of a Fixed Pramlintide: Insulin Dose Ratio on Postprandial Glucose in Type 1 Diabetes Mellitus

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            July 17, 2015

                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Juvenile Diabetes Research Foundation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Joslin Diabetes Center

                            Country arrow
                            Peptide Process CMC
                            Not Confirmed

                            Joslin Diabetes Center

                            Country arrow
                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase IV

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pramlintide (Symlin) for the Treatment of Hypoglycemia Following Gastric Bypass Surgery

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            April 26, 2013

                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase IV

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            AstraZeneca

                            United Kingdom arrow
                            Peptide Process CMC
                            Not Confirmed

                            AstraZeneca

                            United Kingdom arrow
                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Juvenile Diabetes Research Foundation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Effect of Different Fixed Pramlintide:Insulin Dose Ratios on Postprandial Glucose in T1DM

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            October 16, 2012

                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Juvenile Diabetes Research Foundation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            AstraZeneca

                            United Kingdom arrow
                            Peptide Process CMC
                            Not Confirmed

                            AstraZeneca

                            United Kingdom arrow
                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Takeda Pharmaceutical

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study To Examine The Efficacy And Safety Of Pramlintide+Metreleptin In Obese Subjects

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            November 07, 2010

                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Takeda Pharmaceutical

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            University of Colorado, Denver

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                            Peptide Process CMC
                            Not Confirmed

                            University of Colorado, Denver

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                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Amylin Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Effectiveness Study of Pramlintide to Treat Post-Transplant Diabetes Mellitus

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            July 20, 2010

                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Amylin Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Cheryl Rosenfeld

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                            Peptide Process CMC
                            Not Confirmed

                            Cheryl Rosenfeld

                            Country arrow
                            Peptide Process CMC
                            Not Confirmed
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                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Amylin Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy Study of High Dose Symlin to Treat Type 2 Diabetes Mellitus

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            June 04, 2010

                            Lead Product(s) : Pramlintide

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Amylin Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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