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    [{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2014","type":"Inapplicable","leadProduct":"Bamosiran","moa":"Beta-2 adrenergic receptor mRNA","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2010","type":"Inapplicable","leadProduct":"SYL040012","moa":"Beta-2 adrenergic receptor mRNA","graph1":"Ophthalmology","graph2":"Phase I\/ Phase II","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2012","type":"Inapplicable","leadProduct":"SYL040012","moa":"Beta-2 adrenergic receptor mRNA","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2021","type":"Inapplicable","leadProduct":"SYL18001","moa":"Nrarp","graph1":"Ophthalmology","graph2":"Phase I","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2021","type":"Inapplicable","leadProduct":"Tivanisiran Sodium","moa":"siRNA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"Tivanisiran Sodium","moa":"siRNA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"SYL18001 Sodium","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Phase I","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Cell & Gene Therapy","year":"2022","type":"Inapplicable","leadProduct":"SYL1801","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2017","type":"Inapplicable","leadProduct":"SYL1001","moa":"Vanilloid receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2015","type":"Inapplicable","leadProduct":"SYL1001","moa":"Vanilloid receptor","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2011","type":"Inapplicable","leadProduct":"SYL1001","moa":"Vanilloid receptor","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Sylentis \/ Undisclosed"},{"orgOrder":0,"company":"Sylentis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SPAIN","productType":"Oligonucleotide","year":"2013","type":"Inapplicable","leadProduct":"SYL1001","moa":"Vanilloid receptor","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Sylentis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sylentis \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Sylentis \/ Undisclosed"}]

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                            01

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                            Lead Product(s) : SYL1801

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Randomized, Double Masked, Parallel Group, Dose-finding Study to Evaluate SYL1801 in Patients With Neovascul...

                            Details : SYL1801 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Wet Macular Degeneration.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            December 05, 2022

                            Lead Product(s) : SYL1801

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

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                            Lead Product(s) : Tivanisiran Sodium

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety Study of Tivanisiran to Treat Dry Eye

                            Details : Tivanisiran Sodium is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dry Eye Syndromes.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            April 05, 2022

                            Lead Product(s) : Tivanisiran Sodium

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

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                            Lead Product(s) : Tivanisiran Sodium

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tivanisiran for Dry Eye in Subjects With Sjögren's Syndrome

                            Details : Tivanisiran Sodium is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dry Eye Syndromes.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            March 26, 2021

                            Lead Product(s) : Tivanisiran Sodium

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

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                            Lead Product(s) : SYL18001

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sylentis, PharmaMar Group, Initiates a Phase I Clinical Trial with SYL1801 For Retinal Diseases

                            Details : This is a Phase I clinical trial involving 36 healthy volunteers and will be carried out at the Ramón y Cajal University Hospital in Madrid (Spain). This study will evaluate the safety of SYL1801 at different doses, along with the pharmacokinetic profil...

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            March 18, 2021

                            Lead Product(s) : SYL18001

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

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                            Lead Product(s) : SYL18001 Sodium

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye Drops

                            Details : SYL18001 Sodium is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Choroidal Neovascularization.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 04, 2021

                            Lead Product(s) : SYL18001 Sodium

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

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                            Lead Product(s) : SYL1001

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)

                            Details : SYL1001 is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dry Eye Syndromes.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            April 11, 2017

                            Lead Product(s) : SYL1001

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

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                            Lead Product(s) : SYL1001

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dose-finding Study to Assess the Safety and Effect of SYL1001 in Patients With Ocular Pain

                            Details : SYL1001 is a Oligonucleotide drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Eye Pain.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            May 28, 2015

                            Lead Product(s) : SYL1001

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Sylentis

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                            Lead Product(s) : Bamosiran

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            SYL040012, Treatment for Open Angle Glaucoma

                            Details : Bamosiran is a Oligonucleotide drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Glaucoma, Open-Angle.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            September 26, 2014

                            Lead Product(s) : Bamosiran

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

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                            Lead Product(s) : SYL1001

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain

                            Details : SYL1001 is a Oligonucleotide drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Eye Pain.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            January 28, 2013

                            Lead Product(s) : SYL1001

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

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                            Lead Product(s) : SYL040012

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in ...

                            Details : SYL040012 is a Oligonucleotide drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Ocular Hypertension.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            December 03, 2012

                            Lead Product(s) : SYL040012

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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