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Find Clinical Drug Pipeline Developments & Deals by SmartPharm Therapeutics
Initial funding will support project “Gene Mabs: A Scalable, Economic, Gene-Encoded Protective Antibody Platform Against Coronavirus” (HR0011-21-9-0015) to support the development of an STI-2020-encoded Gene MAbTM through Phase 2 clinical studies.
The platform in synergy with Sorrento’s industry-leading fully human G-MAB™ antibody library has the potential to be the engine for the next-generation, cost-effective in vivo production of antibody therapeutics in patients.
Sorrento plans to accelerate the development of multiple candidates for in vivo gene-encoded expression of Sorrento's antibodies, starting with Sorrento's STI-1499, or COVI-GUARD, which is currently moving through preclinical and manufacturing requirements.
The collaboration will use monoclonal antibodies against SARS-CoV-2 virus discovered and generated by Sorrento that will be encoded into a gene using SmartPharm’s non-viral nanoparticle platform.