[{"orgOrder":0,"company":"Siren Biotechnology","sponsor":"Cirm","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Siren Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Siren Biotechnology \/ Cirm","highestDevelopmentStatusID":"4","companyTruncated":"Siren Biotechnology \/ Cirm"},{"orgOrder":0,"company":"Siren Biotechnology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Inapplicable","leadProduct":"SRN-101","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Siren Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Siren Biotechnology \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Siren Biotechnology \/ Inapplicable"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : SRN-101 is a recombinant adeno-associated viral (AAV) vector expressing an engineered cytokine, it is being investigated for the treatment of high-grade gliomas.

                          Product Name : SRN-101

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          November 18, 2024

                          Lead Product(s) : SRN-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : The funding will support the development of novel AAV immuno-gene therapies for cancer, which exhibited potent anti-tumor effects in preclinical models of brain cancer.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          January 11, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Cirm

                          Deal Size : $4.0 million

                          Deal Type : Funding

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