[{"orgOrder":0,"company":"veriNOS operations GmbH","sponsor":"Icon Plc","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"GERMANY","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Ronopterin","moa":"iNOS","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase III","graph3":"veriNOS operations GmbH","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Infusion","sponsorNew":"veriNOS operations GmbH \/ Icon Plc","highestDevelopmentStatusID":"10","companyTruncated":"veriNOS operations GmbH \/ Icon Plc"},{"orgOrder":0,"company":"veriNOS operations GmbH","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"GERMANY","productType":"Miscellaneous","year":"2013","type":"Inapplicable","leadProduct":"Ronopterin","moa":"iNOS","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase III","graph3":"veriNOS operations GmbH","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Infusion","sponsorNew":"veriNOS operations GmbH \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"veriNOS operations GmbH \/ Undisclosed"},{"orgOrder":0,"company":"veriNOS operations GmbH","sponsor":"Winicker Norimed GmbH","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"GERMANY","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Ronopterin","moa":"iNOS","graph1":"Undisclosed","graph2":"Phase I","graph3":"veriNOS operations GmbH","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Infusion","sponsorNew":"veriNOS operations GmbH \/ Winicker Norimed GmbH","highestDevelopmentStatusID":"6","companyTruncated":"veriNOS operations GmbH \/ Winicker Norimed GmbH"},{"orgOrder":0,"company":"Vasopharm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"GERMANY","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Ronopterin","moa":"iNOS","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase III","graph3":"Vasopharm","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Vasopharm \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Vasopharm \/ Undisclosed"},{"orgOrder":0,"company":"Vasopharm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"GERMANY","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Ronopterin","moa":"iNOS","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase III","graph3":"Vasopharm","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Vasopharm \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Vasopharm \/ Undisclosed"},{"orgOrder":0,"company":"Vasopharm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"GERMANY","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Ronopterin","moa":"iNOS","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase III","graph3":"Vasopharm","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Vasopharm \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Vasopharm \/ Undisclosed"}]

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                          01

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : VAS203 (ronopterin) significantly reduces lactate levels in brain microdialysate from TBI patients reflecting energetic stability and neuroprotection during the early vulnerable phase.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 12, 2022

                          Lead Product(s) : Ronopterin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : The NOSTRA trial (NO Synthase in TRAumatic Brain Injury) is a pivotal European trial assessing the efficacy and safety of Ronopterin (VAS203) for the treatment of moderately to severely injured closed head traumatic brain (TBI) injury patients.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 01, 2020

                          Lead Product(s) : Ronopterin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : NOSTRA III is a 220 patient Phase III clinical trial assessing efficacy and safety of Ronopternin (VAS203) for the treatment of moderately to severely injured closed head traumatic brain injuries.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 29, 2020

                          Lead Product(s) : Ronopterin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          veriNOS operations GmbH

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          veriNOS operations GmbH

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : VAS203 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 14, 2016

                          Lead Product(s) : Ronopterin

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Sponsor : Winicker Norimed GmbH

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          veriNOS operations GmbH

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          veriNOS operations GmbH

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : VAS203 is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Brain Injuries, Traumatic.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 08, 2016

                          Lead Product(s) : Ronopterin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase III

                          Sponsor : Icon Plc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          veriNOS operations GmbH

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          veriNOS operations GmbH

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : VAS203 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Brain Injuries, Traumatic.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 16, 2013

                          Lead Product(s) : Ronopterin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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