
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Luvesilocin
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : $133.0 million
Deal Type : Series A Financing
Reunion Announces Final Closing of its Series A Financing
Details : The proceeds will be used to expand the clinical development of RE104, a proprietary, potential best-in-class, patented prodrug of 4-OH-DiPT, into generalized anxiety disorder (GAD).
Product Name : RE104
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 16, 2025
Lead Product(s) : Luvesilocin
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : $133.0 million
Deal Type : Series A Financing

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Lead Product(s) : 14-C RE104
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RE104 Radiolabeled Mass Balance (hAME) Study
Details : 14-C RE104 is a Radiolabelled Compounds drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of unspecified medical condition.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
August 28, 2025
Lead Product(s) : 14-C RE104
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Luvesilocin
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RE104 Safety & Efficacy in Adjustment Disorder in Cancer & Other Illnesses
Details : RE104 is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Adjustment Disorders.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 03, 2025
Lead Product(s) : Luvesilocin
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Luvesilocin
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RE104 Clinical Lactation Study
Details : RE104 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 26, 2024
Lead Product(s) : Luvesilocin
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isoprocin Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Seleni Institute
Deal Size : Undisclosed
Deal Type : Partnership
Reunion Neuroscience And Seleni Institute Partner on Maternal Mental Health
Details : This partnership will grant Reunion Neuroscience access to the Seleni Institute for advancing a mid-stage trial evaluating lead candidate RE104 in Postpartum Depression.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 09, 2024
Lead Product(s) : Isoprocin Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Seleni Institute
Deal Size : Undisclosed
Deal Type : Partnership

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Lead Product(s) : Isoprocin Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Reunion Neuroscience Doses 1st Patient in Phase 2 Trial of RE104 for Postpartum Depression
Details : Reunion Neuroscience's lead product RE104, prodrug of 4-OH-DiPT is being evaluated in the mid-stage clinical trial studies for the treatment of postpartum depression
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 23, 2024
Lead Product(s) : Isoprocin Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isoprocin Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : MPM BioImpact
Deal Size : $103.0 million
Deal Type : Series A Financing
Reunion Neuroscience Announces Series A Financing by MPM BioImpact and Novo Holdings
Details : The financing will bolster the company's mid-stage trial candiditate, particularly focusing on RE104 in postpartum depression, as well as facilitate expansion into additional psychiatric indications.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
May 02, 2024
Lead Product(s) : Isoprocin Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : MPM BioImpact
Deal Size : $103.0 million
Deal Type : Series A Financing

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Lead Product(s) : Luvesilocin
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RE104 Safety and Efficacy Study in Postpartum Depression
Details : RE104 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Depression, Postpartum.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 02, 2024
Lead Product(s) : Luvesilocin
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isoprocin Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : MPM BioImpact
Deal Size : $13.1 million
Deal Type : Acquisition
Reunion Neuroscience Announces US$13.1 Million Take-Private Transaction with MPM BioImpact
Details : MPM BioImpact will develop next-generation solutions for underserved mental health conditions including, RE104, a proprietary, novel, serotonergic psychedelic compound and the only 4-OH-DiPT prodrug in clinical development, being developed for postpartum...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $13.1 million
June 01, 2023
Lead Product(s) : Isoprocin Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : MPM BioImpact
Deal Size : $13.1 million
Deal Type : Acquisition
