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              Vicore Pharma

              • Development Update

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              Robust Effects of VP01 in Human Idiopathic Pulmonary Fibrosis Lung Tissue

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              Lead Product(s): VP01

              Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: C21

              Highest Development Status: Phase II Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable September 25, 2020

              Details:

              Fresh human IPF lung tissue harvested from a patient during lung transplantation showed stable expression of the VP01 target, AT2R, and treatment with clinically relevant concentrations of VP01 caused a dose-dependent decrease of TGFb1.

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