Lead Product(s) : Ketamine Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Keticap® is an oral immediate-release ketamine formulation intended for the treatment of mood disorders such as treatment-resistant depression (TRD) and bipolar depression.
Product Name : Keticap
Product Type : Controlled Substance
Upfront Cash : Inapplicable
December 05, 2023
Lead Product(s) : Ketamine Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ketamine Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Keticap, is a novel oral ketamine immediate-release (IR) formulation to treat major mental health conditions, including treatment-resistant depression.
Product Name : Keticap
Product Type : Controlled Substance
Upfront Cash : Inapplicable
October 24, 2023
Lead Product(s) : Ketamine Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Dimethyltryptamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
First Patient Dosed in Small Pharma's Phase I Study Exploring Intramuscular Administration of SPL026
Details : SPL026, is a proprietary synthetic formulation of N,N-dimethyltryptamine [DMT] fumarate, a psychedelic tryptamine being developed as a supportive therapy for patients with mental health conditions or major depressive disorder.
Product Name : SPL026
Product Type : Controlled Substance
Upfront Cash : Inapplicable
September 01, 2023
Lead Product(s) : Dimethyltryptamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : DSP-2342
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Exscientia Announces Sixth Molecule Created Through Generative AI Platform to Enter Clinical Stage
Details : DSP-2342 is a highly-selective bispecific small molecule with potent dual 5-HT2A and 5-HT7 antagonist activity with broad potential in psychiatric disease.
Product Name : DSP-2342
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 15, 2023
Lead Product(s) : DSP-2342
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Deuterated N,N-dimethyltryptamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
First Subject Dosed in Small Pharma’s First-in-Human Phase I Clinical Trial with SPL028
Details : SPL028, is formulation of deuterated N, N-dimethyltryptamine which offers a similar safety and pharmacological profile to its lead candidate SPL026 or DMT.
Product Name : SPL028
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 15, 2023
Lead Product(s) : Deuterated N,N-dimethyltryptamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : INDV-2000
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Indivior
Deal Size : $20.4 million
Deal Type : Divestment
C4X Discovery Holdings PLC Announces Divestment of Orexin-1 to Indivior for £15.95m
Details : Through the divestment, Indivior gains the proprietary rights to C4XD’s oral Orexin-1 receptor antagonist, INDV-2000 (C4X_3256) for substance use disorder.
Product Name : INDV-2000
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 08, 2023
Lead Product(s) : INDV-2000
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Indivior
Deal Size : $20.4 million
Deal Type : Divestment
Lead Product(s) : Mebufotenin Benzoate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BPL-003, a synthetic intranasal formulation of 5-Methoxy-N, N-Dimethyltryptamine (5-MeO-DMT), which is under development for Treatment Resistant Depression and Alcohol Use Disorder.
Product Name : BPL-003
Product Type : Controlled Substance
Upfront Cash : Inapplicable
November 15, 2022
Lead Product(s) : Mebufotenin Benzoate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Psilocin
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Beckley Psytech
Deal Size : Undisclosed
Deal Type : Acquisition
Details : The acquisition adds ELE-101, a next-generation, short-duration psychedelic ready for Phase 1 clinical trials, to Beckley Psytech’s pipeline. ELE-101 is an intravenous (IV) formulation of psilocin, the active metabolite of psilocybin.
Product Name : ELE-101
Product Type : Controlled Substance
Upfront Cash : Undisclosed
October 24, 2022
Lead Product(s) : Psilocin
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Beckley Psytech
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Mebufotenin Benzoate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Beckley Psytech to Present at 32nd Annual Oppenheimer Healthcare Conference
Details : Phase 1 trial is evaluating the safety and tolerability of a novel formulation of intranasal 5-methoxy-N,N-dimethyltryptamine, in treatment resistant depression (TRD) and other neuropsychiatric indications.
Product Name : BPL-003
Product Type : Controlled Substance
Upfront Cash : Inapplicable
October 03, 2022
Lead Product(s) : Mebufotenin Benzoate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
LB Announces Publication of Phase 1 Clinical Study of LB-102
Details : LB-102, a more lipophilic version of amisulpride, was designed to improve on amisulpride’s notoriously poor membrane (BBB) permeability while matching amisulpride’s binding affinity to the D2/D3 and 5HT7 receptors (critical to the treatment of schizo...
Product Name : LB-102
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 19, 2022
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable