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    [{"orgOrder":0,"company":"Prokarium","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Prokarium \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Prokarium \/ Inapplicable"},{"orgOrder":0,"company":"Prokarium","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2024","type":"Inapplicable","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Prokarium \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Prokarium \/ Inapplicable"},{"orgOrder":0,"company":"Prokarium","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Prokarium \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Prokarium \/ Inapplicable"},{"orgOrder":0,"company":"Prokarium","sponsor":"Prokarium","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Microorganism","year":"2020","type":"Licensing Agreement","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Prokarium \/ Prokarium","highestDevelopmentStatusID":"4","companyTruncated":"Prokarium \/ Prokarium"},{"orgOrder":0,"company":"Prokarium","sponsor":"Simbec Research","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Prokarium \/ Simbec Research","highestDevelopmentStatusID":"6","companyTruncated":"Prokarium \/ Simbec Research"},{"orgOrder":0,"company":"Prokarium","sponsor":"Ginkgo Bioworks","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Partnership","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Discovery","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Prokarium \/ Ginkgo Bioworks","highestDevelopmentStatusID":"2","companyTruncated":"Prokarium \/ Ginkgo Bioworks"},{"orgOrder":0,"company":"Prokarium","sponsor":"Ginkgo Bioworks","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Financing","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Prokarium \/ Ginkgo Bioworks","highestDevelopmentStatusID":"5","companyTruncated":"Prokarium \/ Ginkgo Bioworks"},{"orgOrder":0,"company":"Prokarium","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Prokarium \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Prokarium \/ Inapplicable"},{"orgOrder":0,"company":"Prokarium","sponsor":"Prokarium","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Undisclosed","year":"2022","type":"Licensing Agreement","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Prokarium \/ Prokarium","highestDevelopmentStatusID":"4","companyTruncated":"Prokarium \/ Prokarium"},{"orgOrder":0,"company":"Prokarium","sponsor":"Korea Investment Partners","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Series B Financing","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Prokarium","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Prokarium \/ Korea Investment Partners","highestDevelopmentStatusID":"4","companyTruncated":"Prokarium \/ Korea Investment Partners"}]

    Find Clinical Drug Pipeline Developments & Deals by Prokarium

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                            01

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
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                            Lead Product(s) : ZH9,Inapplicable

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Prokarium Doses First Patient in PARADIGM-1 Trial for Non-Muscle Invasive Bladder Cancer

                            Details : ZH9 is a live attenuated S. enterica serovar Typhi ZH9, a differentiated novel microbial immunotherapy. It is being evaluated in phase 1 clinical trials for non-muscle invasive bladder cancer.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            July 02, 2024

                            Lead Product(s) : ZH9,Inapplicable

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : ZH9,Inapplicable

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase 1/1b Study of ZH9 Treatment in Patients With Non-Muscle Invasive Bladder Cancer

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            December 26, 2023

                            Lead Product(s) : ZH9,Inapplicable

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Ginkgo Bioworks

                            Deal Size : $30.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Prokarium Announces $30 Million Financing to Deliver Lead Program into Clinic and Build Novel Therapeutic Plat...

                            Details : Proceeds will support clinical development of the Company’s lead oncology candidate in non-muscle invasive bladder cancer and accelerate platform discovery.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            September 02, 2023

                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Ginkgo Bioworks

                            Deal Size : $30.0 million

                            Deal Type : Financing

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                            04

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Ginkgo Bioworks

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Prokarium and Ginkgo Bioworks Announce Partnership to Discover Multiple Targets for RNA Therapeutics and Immun...

                            Details : Bactofection, the process of transferring genetic material into a mammalian cell via a bacterium, is an alternative gene delivery system that could deliver therapeutic agents to a patient in RNA-based therapy.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            September 01, 2023

                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Ginkgo Bioworks

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            05

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : ZH9,Inapplicable

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Prokarium Achieves Major Milestone with FDA's IND Approval for Bladder Cancer Program

                            Details : ZH9 is being developed as an intravesical monotherapy treatment for the prevention of recurrences in bladder cancer. The PARADIGM-1 study is expected to enroll in H1 2024 across multiple centers in the United States.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 11, 2023

                            Lead Product(s) : ZH9,Inapplicable

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Salmonella Typhi,Inapplicable

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Prokarium Strengthens Patent Position Through Notice of Allowance of US Patent for Immunotherapy Prime in Comb...

                            Details : Salmonella Typhi delivered orally with an adoptive T cell therapy or an allogeneic or autologous CAR T-cell therapy to increase the therapeutic efficacy of the cell therapy.

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            May 10, 2022

                            Lead Product(s) : Salmonella Typhi,Inapplicable

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Lausanne University Hospital

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Prokarium Exercises Option for an Exclusive Worldwide License for the Use of Salmonella Immunotherapy in the T...

                            Details : Department of Urology at CHUV has generated a robust preclinical data package demonstrating that Prokarium’s proprietary Salmonella bacteria generates quantitatively and qualitatively superior immune responses with different kinetics compared to the st...

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            February 03, 2022

                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Lausanne University Hospital

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            08

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Vesibax,Inapplicable

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Korea Investment Partners

                            Deal Size : $21.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Prokarium Closes $21M Series B Financing Round and Strengthens Board

                            Details : Financing will support the clinical development of Prokarium’s microbial immunotherapy for non-muscle invasive bladder cancer as well as expansion of pipeline across multiple solid tumours.

                            Product Name : Vesibax

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            October 27, 2020

                            Lead Product(s) : Vesibax,Inapplicable

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Korea Investment Partners

                            Deal Size : $21.0 million

                            Deal Type : Series B Financing

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                            09

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed
                            • fda
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                            • WHO-GMP
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                            Lead Product(s) : Salmonella Typhi Ty21a,Inapplicable

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Lausanne University Hospital

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Prokarium Signs an Exclusive Option Agreement with the Lausanne University Hospital for the Treatment of Non-M...

                            Details : Agreement with the Lausanne University Hospital gives Prokarium access to a license to cover the treatment of Non-Muscle Invasive Bladder Cancer patients with intravesical instillations of Salmonella.

                            Product Name : Undisclosed

                            Product Type : Microorganism

                            Upfront Cash : Undisclosed

                            April 28, 2020

                            Lead Product(s) : Salmonella Typhi Ty21a,Inapplicable

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Lausanne University Hospital

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            10

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Prokarium

                            U.S.A arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : ZH9PA,Inapplicable

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Simbec Research

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study to Evaluate the Safety, Tolerability and Immunogenicity of a Potential Enteric Fever Vaccine

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            April 16, 2020

                            Lead Product(s) : ZH9PA,Inapplicable

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Simbec Research

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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