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[{"orgOrder":0,"company":"Embera NeuroTherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Embera NeuroTherapeutics Announces First Subject Dosed in Phase 2 Study of EMB-001 in Cocaine Use Disorder","therapeuticArea":"Psychiatry\/Psychology","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"August 2020","url1":"","url2":"","graph1":"Psychiatry\/Psychology","graph2":"Phase II"},{"orgOrder":0,"company":"HRA Pharma","sponsor":"Esteve Healthcare","pharmaFlowCategory":"D","amount":"$294.2 million","upfrontCash":"$203.3 million","newsHeadline":"Perrigo Receives Binding Offer to Divest its HRA Pharma Rare Diseases Business for up to \u20ac275 Million","therapeuticArea":"Endocrinology","highestDevelopmentStatus":"Approved","country":"FRANCE","productType":"Small molecule","productStatus":"Approved","date":"April 2024","url1":"","url2":"","graph1":"Endocrinology","graph2":"Approved"}]

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            Details:

            Through the divestment, Esteve expand its rare disease business portfolio, by including Metopirone (metyrapone), can be used to treat the signs and symptoms of Cushing's syndrome by lowering high levels of cortisol a hormone produced by the adrenal glands.

            Lead Product(s): Metyrapone

            Therapeutic Area: Endocrinology Product Name: Metopirone

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Esteve Healthcare

            Deal Size: $294.2 million Upfront Cash: $203.3 million

            Deal Type: Divestment April 25, 2024

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            The randomized, double-blind, placebo-controlled Phase 2 clinical trial is supported by funding from the National Institute on Drug Abuse (NIDA) of the National Institutes of Health and will evaluate EMB-001 as a treatment option for patients with cocaine use disorder.

            Lead Product(s): Metyrapone,Oxazepam

            Therapeutic Area: Psychiatry/Psychology Product Name: EMB-001

            Highest Development Status: Phase II Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 31, 2020

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