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Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : OXL001

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Oxilio

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Details : Oxilio has since progressed the product and now signed a significant service contract with Quotient Sciences, a drug development and manufacturing accelerator, to support the formulation development and preparation of clinical trials for OXL001.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 18, 2022

                          Lead Product(s) : OXL001

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Oxilio

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Quotient

                          02

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : The funding will be used to conduct an investigator initiated clinical trial designed to test the feasibility and safety of IMAN therapy administered to patients with metastatic cervical cancer.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          July 29, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Disruptive Technologies Innovation Fund

                          Deal Size : $14.0 million

                          Deal Type : Funding

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                          03

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : The collaboration with ViroCell will help manufacture CAR-T cell therapy products, including AVC-203, an investigational CD19/CD20 dual-targeted cell therapy for the treatment of B-cell malignancies.

                          Product Name : AVC-203

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          July 29, 2025

                          Lead Product(s) : AVC-203

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : AvenCell Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : Boehringer has selected a third drug candidate, which will now advance into IND-enabling studies. The target, OB33, was identified using OBT’s proprietary OGAP-Verify discovery platform.

                          Product Name : OB33

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          July 03, 2025

                          Lead Product(s) : OB33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Boehringer Ingelheim GmbH

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : The net proceeds from the placement will be used to support the clinical development of AKTX-101, is a novel payload is a spliceosome inhibitor. It is being evaluating for treating neoplasms.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          March 03, 2025

                          Lead Product(s) : AKTX-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Paulson Investment Company

                          Deal Size : $7.6 million

                          Deal Type : Private Placement

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                          06

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : The financing will accelerate the lead asset, Jankistomig, a PD1/VEGFR2 bifunctional antibody for multiple solid tumor indications and a pipeline of follow-on bifunctional assets.

                          Product Name : Undisclosed

                          Product Type : Other Large Molecule

                          Upfront Cash : Undisclosed

                          December 19, 2024

                          Lead Product(s) : Jankistomig

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : OrbiMed Advisors

                          Deal Size : $140.0 million

                          Deal Type : Series A Financing

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                          07

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : The agreement aims for clinical trial production of GNX102-ADC in preparation for a planned Phase 1 clinical program investigating the drug technology.

                          Product Name : Undisclosed

                          Product Type : Other Large Molecule

                          Upfront Cash : Undisclosed

                          December 11, 2024

                          Lead Product(s) : GNX102-ADC

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : GlycoNex

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          08

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : The net proceeds from the funding will be used to advance the development of company's Cryptigen immunotherapeutics, discovered by Epitopea’s CryptoMap platform, for cancer.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 09, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Innovate Biopharmaceuticals

                          Deal Size : $0.6 million

                          Deal Type : Funding

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                          09

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : The expanded collaboration will leverage Orbit’s proprietary screening platform to identify and optimize peptide candidates, combined with Evergreen’s expertise in radiopharmaceutical development.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 03, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Evergreen Theragnostics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          10

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : Trogenix lead product candidate is being evaluated in preclinical studies for the treatment of patients with aggressive cancers including glioblastoma.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          November 18, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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