[{"orgOrder":0,"company":"NeurOp","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"NP10679","moa":"GluN2B","graph1":"Neurology","graph2":"Phase I","graph3":"NeurOp","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"NeurOp \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"NeurOp \/ Inapplicable"},{"orgOrder":0,"company":"NeurOp","sponsor":"Seyltx","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Agreement","leadProduct":"Np-10679","moa":"GluN2B","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase I","graph3":"NeurOp","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"NeurOp \/ Seyltx","highestDevelopmentStatusID":"6","companyTruncated":"NeurOp \/ Seyltx"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          NASP
                          Not Confirmed
                          NASP
                          Not Confirmed

                          Details : Seyltx obtained an option to license a GluN2B antagonist portfolio, including the Phase 1 candidate NP10679, to broaden its pipeline for chronic and IPF-associated cough.

                          Product Name : NP10679

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          June 05, 2025

                          Lead Product(s) : Np-10679

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I

                          Sponsor : Seyltx

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          NASP
                          Not Confirmed
                          NASP
                          Not Confirmed

                          Details : FDA granted ODD to NP10679, NMDA receptor inhibitor, demonstrated safety, tolerability and positive pharmacokinetics in Phase 1 studies makes an ideal candidate for prophylactic treatment for SAH.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 12, 2021

                          Lead Product(s) : Np-10679

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          NASP
                          Not Confirmed
                          NASP
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 05, 2019

                          Lead Product(s) : Np-10679

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I

                          Sponsor : National Institute of Neurological Disorders and Stroke | Pharmaron

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          NASP
                          Not Confirmed
                          NASP
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 21, 2018

                          Lead Product(s) : Np-10679

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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