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Find Clinical Drug Development Pipelines & Deals | PipelineProspector
Details :
Under the licensing agreement, Alchemab will be taking the programme through early Phase 1 clinical trials of ATLX-1282 after which Lilly will lead all further development and commercialisation.
Details :
The investment will support development of the Company’s growing pipeline of potent, CNS penetrant therapeutics based on its aggregate-selective degrader molecules known as TRIMTACs.
Details :
The grant will fund a clinical trial of two doses of Tiziana’s novel and patented candidate, intranasal TZLS-401 (foralumab), evaluating the safety of disease improvement in ALS.
Details :
NRG5051 is a first-in-class inhibitor of the mPTP and is designed to penetrate the brain when taken orally. It is being evaluated for the treatment of Parkinson's disease.
Details :
The grant will be used to fund Lario’s preclinical programme investigating selective CaV2.3 calcium channel inhibition as a novel and disease-modifying approach for treatment of Parkinson’s disease.
Details :
The funds raised will be used to complete the preclinical studies for EpilepsyGTx’ lead gene therapy program EPY201, for the treatment of focal refractory epilepsy.
Details :
The funding will be used to support the discovery program focused on developing mPTP inhibitors as novel treatments for amyotrophic lateral sclerosis.
Details :
ACM-002 (S-oxprenolol) has demonstrated slowing disease progression, improvement in survival, attenuation of muscle loss, motor neuron protection in amyotrophic lateral sclerosis (ALS).
Details :
Amphista Therapeutics is developing an orally delivered bifunctional non-cereblon / non-VHL-based protein degrader. It is being evaluated in preclinical studies for neurodegenerative diseases.
Details :
The financing will be used to advance a portfolio small-molecule drugs, including a clinical study in patients with Alzheimer's disease for the lead programme.
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