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Find Neurology Drugs in Phase III Clinical Development in JAPAN
AVP-786 (deudextromethorphan hydrobromide/quinidine sulfate) is a combinational a CYP2D6 inhibitor. It is being evaluated for the treatment of dementia due to Alzheimer’s disease.
NRL-1 (diazepam) nasal spray act as inhibitory effects of gamma-aminobutyric acid (GABA), which is investigated for the treatment of epileptic seizures.
ND0612 is an investigative drug-device combination therapy – a 24 hours/day, continuous subcutaneous infusion of liquid levodopa/carbidopa (LD/CD) for people with Parkinson’s disease (PD) experiencing motor fluctuations.
Lecanemab is an investigational humanized monoclonal antibody for AD. Lecanemab selectively binds and eliminates soluble, toxic amyloid-beta (Aβ) aggregates (protofibrils) that are thought to contribute to the neurotoxicity in AD.
Lecanemab is an investigational humanized monoclonal antibody for Alzheimer’s disease,selectively binds to neutralize and eliminate soluble, toxic amyloid-beta (Aβ) aggregates that are thought to contribute to neurodegenerative process in AD.
In Eisai’s confirmatory Clarity AD study, lecanemab demonstrated consistency of results across scales of cognition and function and subgroups. Lecanemab treatment showed 31% lower risk of converting to next stage of disease by Global CDR assessment (Hazard Ratio: 0.69).
BAN2401 (lecanemab) treatment resulted in highly statistically significant results, reducing clinical decline on the global cognitive and functional scale, compared with placebo at 18 months representing a 27% slowing of decline.
Lecanemab (BAN2401) is an investigational humanized monoclonal antibody for AD that is the result of a strategic research alliance between Eisai and BioArctic.
BAN2401 (Lecanemab) treatment met primary endpoint and reduced clinical decline on global cognitive and functional scale, CDR-SB, compared with placebo at 18 months by 27%, which represents treatment difference score change of -0.45 in analysis of Intent-to-treat population.
BAN2401 (lecanemab) is an investigational humanized monoclonal antibody for Alzheimer's disease,selectively binds to neutralize and eliminate soluble, toxic amyloid-beta (Aβ) aggregates (protofibrils) that are thought to contribute to the neurodegenerative process in AD.