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              Orion Biotechnology

              • Development Update

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              CANADA Canada

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              CFRT 2020

              Participation Not Confirmed

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              Orion’s Phase 3 REFALS Trial Evaluating Oral Levosimendan in Treatment of ALS Patients Did Not Reach its Pre-Specified Endpoints

              Contact the Supplier

              Lead Product(s): Levosimendan

              Therapeutic Area: Neurology Product Name: ODM-109

              Highest Development Status: Phase III Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable July 28, 2020

              Details:

              The primary endpoint of the trial was to show a statistically significant difference between levosimendan and placebo in slow vital capacity (SVC) in supine position at 12 weeks compared to the baseline.

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