
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
Details : Rondecabtagene Autoleucel is a Cell & Gene Therapy drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Lymphoma, Large B-Cell, Diffuse.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
September 23, 2025

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Lead Product(s) : LYL314,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lyell gets RMAT Designation for LYL314 in Refractory Large B-Cell Lymphoma
Details : LYL314 is a next-generation dual-targeting CD19/CD20 CAR T-cell product candidate, being investigated in combination with fludarabine & cyclophosphamide for large B-cell lymphoma (LBCL).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
April 15, 2025
Lead Product(s) : LYL314,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : ImmPACT Bio
Deal Size : $30.0 million
Deal Type : Acquisition
Lyell Immunopharma Completes Acquisition of ImmPACT Bio
Details : Lyell will acquire worldwide rights to ImmPACT’s pipeline, the next- gen CD19/CD20 autologous CAR T-cell therapy, which includes IMPT-314, it is currently in clinical development for B-cell lymphoma.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : $30.0 million
October 31, 2024
Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : ImmPACT Bio
Deal Size : $30.0 million
Deal Type : Acquisition

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Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : ImmPACT Bio
Deal Size : $30.0 million
Deal Type : Acquisition
Lyell Immunopharma Acquires ImmPACT Bio, Refocuses on CAR T-cell Therapy
Details : Lyell will acquire worldwide rights to ImmPACT’s pipeline, the next- gen CD19/CD20 autologous CAR T-cell therapy, which includes IMPT-314, it is currently in clinical development for B-cell lymphoma.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : $30.0 million
October 24, 2024
Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : ImmPACT Bio
Deal Size : $30.0 million
Deal Type : Acquisition

Lyell Reports Dose-dependent Activity from Phase 1 of LYL797, ROR1-targeted CAR-T
Details : LYL797 is a receptor tyrosine kinase-like orphan receptor 1 (ROR1) targeted CAR T‑cell product, being developed for ROR1+ triple negative breast cancer or non-small cell lung cancer.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
June 26, 2024

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Lead Product(s) : IMPT-514
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of IMPT-514 in Active Refractory Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE)
Details : IMPT-514 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Lupus Erythematosus, Systemic.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
December 01, 2023
Lead Product(s) : IMPT-514
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lyell Immunopharma Receives FDA Orphan Drug Designation for LYL845 for the Treatment of Melanoma
Details : LYL845 is an investigational autologous TIL product enhanced with Epi-R manufacturing protocols for patients with relapsed and/or refractory metastatic or locally advanced melanoma, NSCLC and CRC.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
November 09, 2023

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Lead Product(s) : LYL314
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of LYL314 in Aggressive Large B-Cell Lymphoma
Details : LYL314 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Lymphoma, Non-Hodgkin.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
April 24, 2023
Lead Product(s) : LYL314
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

A Study to Investigate LYL845 in Adults With Solid Tumors
Details : LYL845 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Melanoma.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
October 10, 2022

Details : LYL845 is an investigational tumor infiltrating lymphocyte (TIL) therapy enhanced with Lyell’s Epi-R™ technology for patients with relapsed and/or refractory metastatic or locally advanced melanoma and other select solid tumors.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
October 06, 2022
