Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Simcha Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Simcha Therapeutics Licenses Decoy-Resistant IL-18 for Cell Therapy
Details : Under the terms of the agreement, Janssen will develop, manufacture, and commercialize CAR T-based cell therapy candidates with Simcha’s novel proprietary DR-18 for a set number of programs.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
August 01, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Simcha Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Elektrofi
Deal Size : $793.0 million
Deal Type : Collaboration
Elektrofi and Janssen Biotech Collaborate to Develop Formulation Technology Programs
Details : The collaboration focuses on developing an at-home subcutaneous version of a lead oncology asset and up to four additional targets using Elektrofi's formulation technology.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $18.0 million
March 01, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Elektrofi
Deal Size : $793.0 million
Deal Type : Collaboration
Lead Product(s) : Niraparib Tosylate,Abiraterone Acetate,Prednisone
Therapeutic Area : Oncology
Study Phase : Approved FDF
Recipient : Foundation Medicine
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Approves FoundationOne®Liquid CDx as Companion Diagnostic for AKEEGA®
Details : Akeega (niraparib, abiraterone acetate) is a tablet works by inhibiting approved for BRCA-mutated mCRPC in adults. The FDA has approved FoundationOne Liquid CDx as its companion diagnostic.
Product Name : Akeega
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
January 07, 2024
Lead Product(s) : Niraparib Tosylate,Abiraterone Acetate,Prednisone
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Recipient : Foundation Medicine
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LCB84,Undisclosed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : LegoChem Biosciences
Deal Size : $1,700.0 million
Deal Type : Licensing Agreement
LegoChem Biosciences Announces License Agreement for LCB84 Trop2-Targeted ADC
Details : Under the terms of the agreement, LCB will grant Janssen an exclusive, worldwide license for the development and commercialization of LCB84, a Trop2 directed ADC which is currently being investigated for advanced solid tumors.
Product Name : Undisclosed
Product Type : Other Large Molecule
Upfront Cash : $100.0 million
December 26, 2023
Lead Product(s) : LCB84,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : LegoChem Biosciences
Deal Size : $1,700.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Icotrokinra
Therapeutic Area : Immunology
Study Phase : Phase II
Recipient : Protagonist Therapeutics
Deal Size : $987.5 million
Deal Type : Licensing Agreement
Details : Under the Agreement, Janssen is conducting Phase 2b trial of JNJ-2113 (formerly known as PN-235), a first-in-class targeted oral peptide designed to selectively block the IL-23 receptor, in moderately to severely active ulcerative colitis.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : $50.0 million
December 13, 2023
Lead Product(s) : Icotrokinra
Therapeutic Area : Immunology
Highest Development Status : Phase II
Recipient : Protagonist Therapeutics
Deal Size : $987.5 million
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery
Recipient : Biocytogen
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Biocytogen Announces RenLite® Licensing Agreement with Janssen
Details : Janssen will use Biocytogen’s proprietary RenLite® platform to discover, research, develop, manufacture and commercialize fully human antibody therapeutics with a common light chain and other biological therapeutics for an unlimited number of drug tar...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
August 03, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery
Recipient : Biocytogen
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Prizloncabtagene Autoleucel
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Cellular Biomedicine Group
Deal Size : $245.0 million
Deal Type : Collaboration
Details : Through the collaboration, Janssen enhances its portfolio in B-cell malignancies and strengthens its legacy in hematology, by including C-CAR039 (prizloncabtagene autoleucel), a novel bispecific CAR-T therapy targeting both CD19 and CD20 antigens for the...
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 05, 2023
Lead Product(s) : Prizloncabtagene Autoleucel
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Cellular Biomedicine Group
Deal Size : $245.0 million
Deal Type : Collaboration
Lead Product(s) : Aprocitentan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Recipient : Idorsia Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ACT-132577 (aprocitentan) is a dual endothelin receptor antagonist, which potently inhibits the binding of ET-1 to ETA and ETB receptors. It has a mechanism of action that is ideally suited for the pathophysiology of resistant hypertension.
Product Name : Tryvio
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 31, 2023
Lead Product(s) : Aprocitentan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Recipient : Idorsia Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Icotrokinra
Therapeutic Area : Dermatology
Study Phase : Phase II
Recipient : Protagonist Therapeutics
Deal Size : $990.0 million
Deal Type : Collaboration
Details : The collaboration aims for the co-development and commercialization of JNJ-2113, a novel, first and only oral IL-23 receptor antagonist peptide, in patients with moderate-to-severe psoriasis.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : $50.0 million
January 11, 2023
Lead Product(s) : Icotrokinra
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Recipient : Protagonist Therapeutics
Deal Size : $990.0 million
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Lava Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the collaboration, Janssen has chosen a lead gamma-delta T-cell engager bispecific antibody candidate aimed at an undisclosed tumor-associated antigen for further development towards clinical settings for the treatment of cancer.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 06, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Lava Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration