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              Implicit Bioscience

              • Development Update

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              AUSTRALIA Australia

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              ASCO 2020

              Participation Not Confirmed

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              Clinical trial in COVID-19 patients tests anti-inflammatory drug developed 25 years ago at Scripps Research

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              Lead Product(s): IC14

              Therapeutic Area: Infections and Infectious Diseases

              Highest Development Status: Undisclosed Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable April 29, 2020

              Details:

              The trial will assess if IC14 can temper the immune system’s response to coronavirus infection of the lungs, thus preventing dangerous levels of inflammation.

              Mesoblast

              • Development Update

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              AUSTRALIA Australia

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              ASCO 2020

              Participation Not Confirmed

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              Mesoblast To Evaluate Anti-Inflammatory Cell Therapy Remestemcel-L

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              Lead Product(s): Remestemcel-L

              Therapeutic Area: Infections and Infectious Diseases

              Highest Development Status: Undisclosed Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable March 10, 2020

              Details:

              A clinical study conducted in China reported that allogeneic MSCs cured or significantly improved functional outcomes in all seven treated patients with severe COVID-19 pneumonia.

              Biotron

              • Development Update

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              AUSTRALIA Australia

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              ASCO 2020

              Participation Not Confirmed

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              Biotron’s Compound BIT036 as an antiviral for COVID-19

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              Lead Product(s): Cinnamoylguanidine

              Therapeutic Area: Infections and Infectious Diseases

              Highest Development Status: Undisclosed Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable March 07, 2020

              Details:

              Biotron was first to demonstrate that the E Protein within SARS is a viroporin, and has since developed compounds that inhibit viroporin activity.

              Novotech

              • Development Update

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              AUSTRALIA Australia

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              ASCO 2020

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              Novotech Wins Cro Contract For Komipharm Coronavirus Covid-19 Clinical Trial In South Korea

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              Lead Product(s): Panaphix

              Therapeutic Area: Infections and Infectious Diseases

              Highest Development Status: Undisclosed Product Type: Undisclosed

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable March 06, 2020

              Details:

              The company said it seeks to expand the use of Panaphix to cover COVID-19 treatment through this proposed clinical trial.

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