Infections and Infectious Diseases | Preclinical Developments | CANADA

IGY Life Sciences

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IGY Life Sciences Partners with MMS Holdings to Develop Novel COVID-19 Antibody Treatment

Lead Product(s): IgY-110

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Large molecule

Partner/Sponsor/Collaborator: MMS Holdings

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership June 08, 2020

Details:

The partnership aims at further developing IgY-110, an anti-CoV-2 therapeutic antibody with a focus on a nasal spray application. This novel approach of an IgY antibody in a nasal spray will be complementary to any vaccine developed.

Resverlogix Corp

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Resverlogix Plans Covid-19 Clinical Trial Program Launch

Lead Product(s): Apabetalone

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 01, 2020

Details:

An additional step will be to proceed with an open-label study to assess the safety and efficacy of a clinical course of oral apabetalone in hospitalized subjects with 2019-nCoV infection on top of standard of care compared to standard of care alone.

IMV

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IMV Announces Selection of a Vaccine Candidate Against COVID-19 to Advance Into Human Clinical Studies

Lead Product(s): DPX-COVID-19

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 21, 2020

Details:

Majority of 23 peptide epitopes selected by IMV demonstrated robust antibody responses in an animal model after first and second dose in DPX formulation without any additional adjuvant.

Tetra BioPharma

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Tetra Bio-Pharma Provides PPP003 Inflammatory Cytokine Reduction Drug Program

Lead Product(s): Cannabidiol

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 06, 2020

Details:

Tetra Bio-Pharma has completed the modifications to the nonclinical safety study of PPP003 to ensure the launch of a Phase 1 trial in healthy volunteers.

Tetra BioPharma

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Tetra Bio-Pharma Announces Drug Candidate as Potential Therapy for Managing Cytokine Release Syndrome

Lead Product(s): Cannabidiol

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 27, 2020

Details:

Preclinical proof of concept of PPP003 as potential drug candidate for sepsis demonstrated Tetra to develop PPP003 as potential drug therapy for the battle against COVID-19.

Medicago

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Medicago Announces Production of a Viable Vaccine Candidate for COVID-19

Lead Product(s): Virus-Like Particle

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 12, 2020

Details:

Medicago has successfully produced a Virus-Like Particle (VLP) of the coronavirus just 20 days after obtaining the SARS-CoV-2 (virus causing the COVID-19 disease) gene.

XPhyto

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XPhyto Therapeutics Initiates Infectious Disease Programs

Lead Product(s): Cannabigerol

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 03, 2020

Details:

The programs include in-vitro study of thin film delivery of cannabigerol and quercetin for potential anti-bacterial and anti-viral treatments as well as development of point-of-care sensor-film.

Arch Biopartners

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Arch Scientist Publishes Data on the Pre-Clinical Efficacy of AB569 in Killing of Drug Resistant Bacteria

Lead Product(s): Sodium Nitrite,Edetate Disodium

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 21, 2020

Details:

The paper demonstrates key data on the synergistic effects of acidified sodium nitrite and EDTA (active ingredients of AB569) on destroying all bacteria

Mannin Research

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Q BioMed Partner Mannin Research Developing Potential Treatment for Patients Infected with Coronavirus

Lead Product(s): Undisclosed

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Undisclosed

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 20, 2020

Details:

Platform has been awarded grants from Canada and Europe for its development of therapeutics; additional grant submitted to the STTR program administered by the U.S. National Institutes of Health.

Appili Therapeutics

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Researchers Present Positive Interim Data on Appili Therapeutics’ ATI-1701 Biodefense Program at 2020 ASM Biothreats

Lead Product(s): ATI-1701

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Preclinical Product Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 28, 2020

Details:

These interim results add to a growing body of evidence supporting advanced development of ATI-1701 as a medical countermeasure against one of the most significant bioterrorism threats.

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Find Drugs for Infections and Infectious Diseases in Preclinical Development in CANADA

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IGY Life Sciences

IGY Life Sciences Partners with MMS Holdings to Develop Novel COVID-19 Antibody Treatment

Resverlogix Corp

Resverlogix Plans Covid-19 Clinical Trial Program Launch

IMV

IMV Announces Selection of a Vaccine Candidate Against COVID-19 to Advance Into Human Clinical Studies

Tetra BioPharma

Tetra Bio-Pharma Provides PPP003 Inflammatory Cytokine Reduction Drug Program

Tetra BioPharma

Tetra Bio-Pharma Announces Drug Candidate as Potential Therapy for Managing Cytokine Release Syndrome

Medicago

Medicago Announces Production of a Viable Vaccine Candidate for COVID-19

XPhyto

XPhyto Therapeutics Initiates Infectious Disease Programs

Arch Biopartners

Arch Scientist Publishes Data on the Pre-Clinical Efficacy of AB569 in Killing of Drug Resistant Bacteria

Mannin Research

Q BioMed Partner Mannin Research Developing Potential Treatment for Patients Infected with Coronavirus

Appili Therapeutics

Researchers Present Positive Interim Data on Appili Therapeutics’ ATI-1701 Biodefense Program at 2020 ASM Biothreats