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    [{"orgOrder":0,"company":"ACM Biolabs","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SINGAPORE","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"ACM-001","moa":"Beta-1 receptor","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"ACM Biolabs","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ACM Biolabs \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"ACM Biolabs \/ Undisclosed"},{"orgOrder":0,"company":"ACM Biolabs","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SINGAPORE","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Pindolol","moa":"Beta-2 adrenergic receptor | Beta-1 adrenergic receptor","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"ACM Biolabs","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"ACM Biolabs \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"ACM Biolabs \/ Undisclosed"},{"orgOrder":0,"company":"Tychan","sponsor":"Duke-NUS Graduate Medical School | Singapore Clinical Research Institute | National University of Singapore | National University Hospital, Singapore","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SINGAPORE","productType":"Antibody, Unconjugated","year":"2018","type":"Inapplicable","leadProduct":"Tyzivumab","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Tychan","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tychan \/ Duke-NUS Graduate Medical School | Singapore Clinical Research Institute | National University of Singapore | National University Hospital, Singapore","highestDevelopmentStatusID":"6","companyTruncated":"Tychan \/ Duke-NUS Graduate Medical School | Singapore Clinical Research Institute | National University of Singapore | National University Hospital, Singapore"},{"orgOrder":0,"company":"Tychan","sponsor":"Singapore Clinical Research Institute | Duke-NUS Graduate Medical School","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SINGAPORE","productType":"Antibody, Unconjugated","year":"2018","type":"Inapplicable","leadProduct":"Tyzivumab","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Tychan","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tychan \/ Singapore Clinical Research Institute | Duke-NUS Graduate Medical School","highestDevelopmentStatusID":"6","companyTruncated":"Tychan \/ Singapore Clinical Research Institute | Duke-NUS Graduate Medical School"},{"orgOrder":0,"company":"Tychan","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SINGAPORE","productType":"Antibody, Unconjugated","year":"2020","type":"Inapplicable","leadProduct":"TY014","moa":"Viral envelope protein epitope","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Tychan","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Tychan \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Tychan \/ Undisclosed"}]

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                            01

                            ACM Biolabs

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                            AIChE Annual Meeting
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                            ACM Biolabs

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                            Lead Product(s) : Pindolol

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            As part of 'Operation Nasal Vaccine' to Counter COVID-19 spread, ACM-001 Booster Vaccine Administered to First...

                            Details : The spike-protein component of ACM-001 is modeled after the immune-evasive beta variant. In animal studies the clinical vaccine candidate was safe and generated a protective immune response against the beta-variant and ancestral form of SARS-2.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 29, 2022

                            Lead Product(s) : Pindolol

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            ACM Biolabs

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                            AIChE Annual Meeting
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                            ACM Biolabs

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                            Lead Product(s) : ACM-001

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Booster Dose Study to Assess the Safety and Immunogenicity of ACM-001 Administered Intramuscularly or Intranas...

                            Details : ACM-001 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of COVID-19.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 23, 2022

                            Lead Product(s) : ACM-001

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Tychan

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                            AIChE Annual Meeting
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                            Tychan

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                            Lead Product(s) : TY014

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            NEJM Study Demonstrates Safety and Efficacy of mAb to Treat Yellow Fever

                            Details : Data published in the New England Journal of Medicine demonstrate that TY014 was not only safe and well tolerated at the highest doses tested, but also completely eradicated the yellow fever virus in the bloodstream of all participants within 48 hours of...

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            July 30, 2020

                            Lead Product(s) : TY014

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Tychan

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                            Tychan

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                            Lead Product(s) : TY027

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety of TY027, a Treatment for COVID-19, in Humans

                            Details : TY027 is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of COVID-19.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            June 12, 2020

                            Lead Product(s) : TY027

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Tychan

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                            AIChE Annual Meeting
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                            Tychan

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                            Lead Product(s) : TY027

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Temasek-backed Tychan to Start Human Trials Next Week for COVID-19 Treatment

                            Details : The study to be conducted by Tychan is meant to determine the safety and effectiveness of TY027, a monoclonal antibody or immune system protein that specifically targets Sars-CoV-2, the virus that causes Covid-19.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            June 10, 2020

                            Lead Product(s) : TY027

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Tychan

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                            Tychan

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                            Lead Product(s) : Tyzivumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Singapore Clinical Research Institute | Duke-NUS Graduate Medical School

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Safety and Tolerability of an Antibody Against Zika Virus (Tyzivumab) in ZIKV Infected Patients

                            Details : Tyzivumab is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Zika Virus Infection.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            December 17, 2018

                            Lead Product(s) : Tyzivumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Singapore Clinical Research Institute | Duke-NUS Graduate Medical School

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Tychan

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                            Tychan

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                            Lead Product(s) : Tyzivumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Duke-NUS Graduate Medical School | Singapore Clinical Research Institute | National University of Singapore | National University Hospital, Singapore

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety and Tolerability of an Antibody Against Zika Virus (Tyzivumab) in Humans

                            Details : Tyzivumab is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Zika Virus Infection.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            February 23, 2018

                            Lead Product(s) : Tyzivumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Duke-NUS Graduate Medical School | Singapore Clinical Research Institute | National University of Singapore | National University Hospital, Singapore

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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