Drugs in Dev.
Infections and Infectious Diseases
Phase I
Canada 
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Lead Product(s) : Nitric Oxide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Nitric Oxide Releasing Mouthwash (NORM) for the Management of Oropharyngeal Candidiasis
Details : Nitric Oxide is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Candidiasis, Oral.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 07, 2023
Lead Product(s) : Nitric Oxide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : COVID-19 mRNA Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Shulan (Hangzhou) Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase 1 Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine
Details : COVID-19 mRNA Vaccine is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of COVID-19.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
November 02, 2023
Lead Product(s) : COVID-19 mRNA Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Shulan (Hangzhou) Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Metronidazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ATI-1501 (metronidazole) is a taste-masked liquid oral reformulation of metronidazole which effectively treats Clostridium difficile infection (CDI) in children by inhibiting protein synthesis by interacting with DNA leading cell death in susceptible org...
Product Name : Undisclosed
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
May 24, 2023
Lead Product(s) : Metronidazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Poria Cocos Mushroom Extract,Aloe vera,Rosemary Extract
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : UP360 is a naturally-derived extracts from both the Poria cocos mushroom and rosemary as well as Aloe vera gel powder. The UP360 produces antioxidant, anti-inflammatory, and immunomodulatory effects.
Product Name : Undisclosed
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
May 03, 2023
Lead Product(s) : Poria Cocos Mushroom Extract,Aloe vera,Rosemary Extract
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Metronidazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Appili Therapeutics Announces that FDA Accepts The ATI-1501 NDA
Details : ATI-1501 (metronidazole) is a taste-masked liquid oral reformulation of metronidazole which effectively treats Clostridium difficile infection (CDI) in children by inhibiting protein synthesis by interacting with DNA leading cell death in susceptible org...
Product Name : Undisclosed
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
February 08, 2023
Lead Product(s) : Metronidazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Metronidazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ATI-1501 (metronidazole) is a taste-masked liquid oral reformulation of metronidazole which effectively treats Clostridium difficile infection (CDI) in children by inhibiting protein synthesis by interacting with DNA leading cell death in susceptible org...
Product Name : Undisclosed
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
January 13, 2023
Lead Product(s) : Metronidazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Acacia Catechu,Scutellaria Baicalensis
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : UP446, a natural health ingredient developed by Unigen, contains Acacia catechu and Scutellaria baicalensis, botanicals with antioxidant and anti-inflammatory properties; however, this is the first study to examine these ingredients using a human vaccine...
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
December 06, 2022
Lead Product(s) : Acacia Catechu,Scutellaria Baicalensis
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ATI-2307
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Long Zone Holdings Inc.
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Appili shall grant LZH an exclusive license to commercialize Appili’s future approved products in Latin America, Canada, and Israel (collectively, the “Territory”), excluding ATI-1501 in Latin America, which was recently licensed to existing partne...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 29, 2022
Lead Product(s) : ATI-2307
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Long Zone Holdings Inc.
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : Metronidazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Saptalis pharm
Deal Size : Undisclosed
Deal Type : Agreement
Appili Therapeutics Expands ATI-1501 Commercial Agreement with Partner Saptalis Pharmaceuticals
Details : Under the terms of the amended agreement, Saptalis will assume responsibility for development and commercialization of ATI-1501 in Europe and Latin America (collectively, the “Expanded Territories”).
Product Name : Undisclosed
Product Type : Plant Extract/Herbal
Upfront Cash : Undisclosed
February 08, 2022
Lead Product(s) : Metronidazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Saptalis pharm
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : ATI-2307
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : The Lind Partners
Deal Size : $4.0 million
Deal Type : Financing
Appili Therapeutics Announces Update to Funding Agreement With The Lind Partners
Details : Appili Therapeutics will use the proceed from Lind, to expand and advance it's diversified anti-infective pipeline of four potential products through key development milestones in 2022, including a Phase 2 start for novel antifungal ATI-2307.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 22, 2021
Lead Product(s) : ATI-2307
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : The Lind Partners
Deal Size : $4.0 million
Deal Type : Financing
