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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : Equillium intends to use the proceeds to fund the further development of EQ504, an investigational potent and selective aryl hydrocarbon receptor (AhR) modulator.

                          Product Name : EQ504

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          August 11, 2025

                          Lead Product(s) : EQ504

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : ADAR1 Capital Management

                          Deal Size : $50.0 million

                          Deal Type : Financing

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                          02

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : Under the terms of the agreement, Otsuka is granted an exclusive license to develop, manufacture, and commercialize HBM7020, a BCMAxCD3 bispecific T-cell engager globally, excluding Greater China.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $47.0 million

                          June 22, 2025

                          Lead Product(s) : HBM7020

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Otsuka Pharmaceutical

                          Deal Size : $670.0 million

                          Deal Type : Licensing Agreement

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                          03

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : CLN-978 is a novel, differentiated and highly potent CD19xCD3 bispecific T cell engager. It is being evaluated for the treatment of Sjogren's Syndrome.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 29, 2025

                          Lead Product(s) : CLN-978

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : ATI-052 is an investigational, potential best-in-class anti-TSLP/IL-4R bispecific monoclonal antibody being developed to treat certain immuno-inflammatory diseases.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 22, 2025

                          Lead Product(s) : ATI-052

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : NX-0479 is a highly optimized, selective, oral degrader of IRAK4,being investigated in inflammation, in both rheumatology and dermatology.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 17, 2025

                          Lead Product(s) : NX-0479

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Gilead Sciences

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : CLN-978 is a novel, highly potent, half-life extended CD19xCD3 bispecific T cell engager construct. It is being evaluated for rheumatoid arthritis.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 16, 2025

                          Lead Product(s) : CLN-978

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : The financing aims to advance the clinical development of company's lead candidate, which is being evaluated for the treatment of Graves Disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 08, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Bain Capital Life Sciences

                          Deal Size : $121.0 million

                          Deal Type : Series A Financing

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                          08

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : ALLO-329, an investigational dual-targeted CD19/CD70 allogeneic CAR T, has received FTD from the FDA for the treatment of adult patients with systemic lupus erythematous.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 07, 2025

                          Lead Product(s) : ALLO-329

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : S‑8484 is an engineered IgE protease works by rapid and sustained degradation of IgE in plasma and on IgE B cell receptors. It is being investigated for allergic disease.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          February 28, 2025

                          Lead Product(s) : S‑8484

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : FDA has cleared its Investigational New Drug (IND) application for a rheumatology basket study of ALLO-329, an investigational allogeneic CAR T product for autoimmune diseases.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 28, 2025

                          Lead Product(s) : ALLO-329

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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