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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : Under the licensing agreement, iBio will be solely responsible for the research and development, manufacturing and commercialization of IBIO-600 for obesity and cardiometabolic treatment.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : $0.7 million

                          January 03, 2025

                          Lead Product(s) : IBIO-600

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Recipient : AstralBio

                          Deal Size : $28.7 million

                          Deal Type : Licensing Agreement

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                          02

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : RTX-003 is a targeted anti-CD25 monoclonal antibody that binds CD25 without blocking IL-2 on the high-affinity IL-2 receptor alpha on T regulatory (T reg) cells, and designed to induce T reg cell death, thus supporting tumor immunity.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : $1.0 million

                          September 21, 2022

                          Lead Product(s) : RTX-003

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : RubrYc Therapeutics

                          Deal Size : $6.0 million

                          Deal Type : Acquisition

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                          03

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : Early functional testing of mouse antisera from IBIO-201 immunized mice demonstrates the presence of antibodies that interfere with the binding of SARS-CoV-2 spike protein sequences to human ACE2 in ex vivo assays.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          October 08, 2020

                          Lead Product(s) : IBIO-201

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : Under the MSAs, IDRI will support pre-clinical development and provide clinical trial oversight, while iBio will provide process development and manufacturing services to IDRI, as needed.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          October 04, 2020

                          Lead Product(s) : IBIO-200

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : Infectious Disease Research Institute

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : Under the terms of the agreement, iBio obtained an exclusive license to Planet’s ACE2-Fc. Planet is eligible to receive certain pre-specified payments upon achievement of clinical development milestones.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          August 28, 2020

                          Lead Product(s) : ACE2-Fc

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : Planet Biotechnology

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          06

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : IBM Watson Health has received interest in the offering from numerous hospitals, sponsors, contract research organizations and academic institutions, and is currently enabling 15 COVID-19 disease trials.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          June 24, 2020

                          Lead Product(s) : IBIO-200

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : IBM Watson Health

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          07

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : The new subunit vaccine (“IBIO-201”) combines antigens derived from the SARS-CoV-2 spike protein fused with the Company’s patented lichenase booster molecule (“LicKM”), which is designed to enhance immune response.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          April 06, 2020

                          Lead Product(s) : IBIO-201

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : iBio created its proprietary VLP candidates using its FastPharming System™. then deployed this plant-based expression platform’s rapid production capabilities to deliver VLPs.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          March 26, 2020

                          Lead Product(s) : IBIO-200

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : Texas A&M University System laboratories

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          09

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : iBio plans to transfer its proprietary FastPharming Manufacturing System™ to AzarGen in South Africa for production of critical biological medicines for the African continent.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          March 26, 2020

                          Lead Product(s) : Rituximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Sponsor : Azargen Biotechnologies

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          10

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : iBio created its SARS-CoV-2 Virus-Like Particle-based constructs in just a few weeks using its FastPharming System™ to produce the nanoparticles in, and purify them from, plants.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          March 18, 2020

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Undisclosed

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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