[{"orgOrder":0,"company":"Praxis Pharmaceutical","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"SPAIN","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Relutrigine","moa":"NaV Channel","graph1":"Genetic Disease","graph2":"Phase I","graph3":"Praxis Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Praxis Pharmaceutical \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Praxis Pharmaceutical \/ Undisclosed"},{"orgOrder":0,"company":"Connecta therapeutics","sponsor":"Hospital del Mar Research Institute (IMIM) | Adknoma | Ministry of Science and Innovation, Spain","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"SPAIN","productType":"Undisclosed","year":"2024","type":"Inapplicable","leadProduct":"CTH120","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Phase I","graph3":"Connecta therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Connecta therapeutics \/ Hospital del Mar Research Institute (IMIM) | Adknoma | Ministry of Science and Innovation, Spain","highestDevelopmentStatusID":"6","companyTruncated":"Connecta therapeutics \/ Hospital del Mar Research Institute (IMIM) | Adknoma | Ministry of Science and Innovation, Spain"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Lead Product(s) : CTH120

                          Therapeutic Area : Genetic Disease

                          Study Phase : Phase I

                          Sponsor : Hospital del Mar Research Institute (IMIM) | Adknoma | Ministry of Science and Innovation, Spain

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : CTH120 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Fragile X Syndrome.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          July 01, 2024

                          Lead Product(s) : CTH120

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Sponsor : Hospital del Mar Research Institute (IMIM) | Adknoma | Ministry of Science and Innovation, Spain

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : PRAX-562 is a first selective persistent sodium current blocker. Praxis plans to initiate a Phase 2 clinical trial in the first half of 2022 to explore the potential for PRAX-562 to treat a range of rare pediatric DEEs, including SCN2A-DEE and SCN8A-DEE.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 30, 2021

                          Lead Product(s) : Relutrigine

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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