Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
DermBiont Announces New Indications for SM-020 in Basal Cell Carcinoma After Positive Data
Details : SM-020, a first-in-class, patient-applied, and topical kinase inhibitor, for the development of locally advanced basal cell carcinoma and prevention of BCC in Gorlin Syndrome patients.
Product Name : SM-020
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 15, 2024
Lead Product(s) : SM-020
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Double Point Ventures
Deal Size : $35.2 million
Deal Type : Series B Financing
Details : The net proceeds will be used to advance the clinical development of SM-020 for the treatment of seborrheic keratoses and SM-030 for the treatment of melasma and other hyperpigmentation disorders of the skin.
Product Name : SM-020
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 24, 2023
Lead Product(s) : SM-020
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Double Point Ventures
Deal Size : $35.2 million
Deal Type : Series B Financing
Lead Product(s) : Ruboxistaurin
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SM-030 (ruboxistaurin) is a first-in-class selective and potent topical gel which is designed to inhibit PKCβ, which is the key and final enzyme in the melanin synthesis pathway, thus reduces the production of excess epidermal melanin.
Product Name : SM-030
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 30, 2023
Lead Product(s) : Ruboxistaurin
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SM-020
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SM-020 is the first and only highly selective topical treatment that results in natural apoptosis of SK cells without cytotoxicity to healthy, normal keratinocytes.
Product Name : SM-020
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 23, 2022
Lead Product(s) : SM-020
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruboxistaurin
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : DermBiont
Deal Size : Undisclosed
Deal Type : Acquisition
Details : Acquisition of clinical-stage biotechnology company Chromaderm by DermBiont, will accelerate the development of Chromaderm’s drug candidate, ruboxistaurin (SM-030), topical formulation of the first and only targeted drug to treat skin hyperpigmentation...
Product Name : SM-030
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 21, 2021
Lead Product(s) : Ruboxistaurin
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : DermBiont
Deal Size : Undisclosed
Deal Type : Acquisition