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X","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase III","graph3":"Insel Gruppe AG, University Hospital Bern","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Insel Gruppe AG, University Hospital Bern \/ Daiichi Sankyo","highestDevelopmentStatusID":"10","companyTruncated":"Insel Gruppe AG, University Hospital Bern \/ Daiichi Sankyo"},{"orgOrder":0,"company":"Sint Maartenskliniek","sponsor":"ZonMw | RSMK | Tiofarma | Dutch Arthritis Foundation Reuma Nederland","pharmaFlowCategory":"DU","therapeuticArea":"Musculoskeletal","country":"","productType":"Plant Extract\/Herbal","year":"2024","type":"Inapplicable","leadProduct":"Colchicine","moa":"||Tubulin","graph1":"Musculoskeletal","graph2":"Phase III","graph3":"Sint Maartenskliniek","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Sint Maartenskliniek \/ ZonMw | RSMK | Tiofarma | Dutch Arthritis Foundation Reuma Nederland","highestDevelopmentStatusID":"10","companyTruncated":"Sint Maartenskliniek \/ ZonMw | RSMK | Tiofarma | Dutch Arthritis Foundation Reuma Nederland"},{"orgOrder":0,"company":"Dyve Biosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Colchicine","moa":"||pH","graph1":"Rheumatology","graph2":"Phase II","graph3":"Dyve Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Transdermal Cream","sponsorNew":"Dyve Biosciences \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Dyve Biosciences \/ Inapplicable"},{"orgOrder":0,"company":"Hamad Medical Corporation","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Plant Extract\/Herbal","year":"2021","type":"Inapplicable","leadProduct":"Colchicine","moa":"||Tubulin","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Hamad Medical Corporation","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hamad Medical Corporation \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Hamad Medical Corporation \/ Inapplicable"},{"orgOrder":0,"company":"Hamilton Health Sciences","sponsor":"Hamilton Academic Health Sciences Organization | St. Joseph's Health Care London","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Plant Extract\/Herbal","year":"2024","type":"Inapplicable","leadProduct":"Colchicine","moa":"||Tubulin","graph1":"Nephrology","graph2":"Phase I","graph3":"Hamilton Health Sciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Hamilton Health Sciences \/ Hamilton Academic Health Sciences Organization | St. Joseph's Health Care London","highestDevelopmentStatusID":"6","companyTruncated":"Hamilton Health Sciences \/ Hamilton Academic Health Sciences Organization | St. Joseph's Health Care London"},{"orgOrder":0,"company":"PK MED","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"FRANCE","productType":"Plant Extract\/Herbal","year":"2024","type":"Inapplicable","leadProduct":"Colchicine","moa":"||Beta-tubulin polymerisation","graph1":"Rheumatology","graph2":"IND Enabling","graph3":"PK MED","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Intra-articular Injection, Prolonged Release","sponsorNew":"PK MED \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"PK MED \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals for Colchicine, Colchicum autumnale

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Colchicine tablets inhibits the beta tubulin polymerisation, which is indicated for prophylaxis of gout flares in adults and Familial Mediterranean fever (FMF) in adults and children 4 years or older

                          Product Name : Colcrys-Generic

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          November 03, 2022

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Strides Pharma Science

                          02

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Colchicine capsule (0.6 mg) is a generic version of Hikma's Mitigare has been approved by USFDA, it is indicated for prophylaxis of gout flares in adults.

                          Product Name : Mitigare-Generic

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          April 30, 2021

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Granules India

                          03

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The Colcrys® (colchicine) brand and generic market had U.S. sales of approximately $491 million MAT for the most recent twelve months ending in March 2020 according to IQVIA Health.

                          Product Name : Colchicine-Generic

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          December 06, 2020

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Dr Reddy Company Banner

                          04

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Colchicine capsules inhibits the beta tubulin polymerisation into microtubules, which is indicated for the prophylaxis of gout flares in adults patients.

                          Product Name : Mitigare-Generic

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          November 02, 2020

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Granules India

                          05

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Colchicine tablets inhibits the beta tubulin polymerisation, which is indicated for prophylaxis of gout flares in adults and Familial Mediterranean fever (FMF) in adults and children 4 years or older

                          Product Name : Mitigare-Generic

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          June 02, 2020

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Granules India

                          06

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Gloperba (colchicine) disrupts the polymerization of β-tubulin into microtubules, thereby preventing the activation, degranulation & migration of neutrophils to sites of inflammation in pericarditis.

                          Product Name : Gloperba

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          April 16, 2025

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Undisclosed

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Under the licensing agreement, Scilex will be responsible for the commercialization of Gloperba (Colchicine) only in the U.S. It is indicated for the treatment of gout flares in adults.

                          Product Name : Gloperba

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Undisclosed

                          January 16, 2025

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Approved FDF

                          Sponsor : Scilex Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          08

                          Vivek Reddy

                          Country arrow
                          EPSC
                          Not Confirmed

                          Vivek Reddy

                          Country arrow
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          January 09, 2025

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase IV

                          Sponsor : Boston Scientific

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Gloperba (colchicine) liquid oral solution is a USFDA approved, tubulin inhibitor small molecule drug candidate which is indicated for prophylaxis of gout flares in adults.

                          Product Name : Gloperba

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          August 29, 2024

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Sint Maartenskliniek

                          Country arrow
                          EPSC
                          Not Confirmed

                          Sint Maartenskliniek

                          Country arrow
                          EPSC
                          Not Confirmed

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Musculoskeletal

                          Study Phase : Phase III

                          Sponsor : ZonMw | RSMK | Tiofarma | Dutch Arthritis Foundation Reuma Nederland

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          August 29, 2024

                          Lead Product(s) : Colchicine,Inapplicable

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase III

                          Sponsor : ZonMw | RSMK | Tiofarma | Dutch Arthritis Foundation Reuma Nederland

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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