Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : 225-Ac CLR 121225
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Isotope Technologies Munich
Deal Size : Undisclosed
Deal Type : Agreement
Cellectar Biosciences and ITM Enter Supply Agreement for GMP-Grade Actinium-225
Details : The agreement will support the clinical development of Cellectar’s actinium-labeled PLE radiopharmaceuticals, including its Phase 1-ready compound, CLR 121225, for the treatment of solid tumors.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
September 11, 2025
Lead Product(s) : 225-Ac CLR 121225
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Isotope Technologies Munich
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : CLR 125
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Ladenburg Thalmann & Co
Deal Size : $6.9 million
Deal Type : Public Offering
Cellectar Biosciences Announces Closing of $6.9 Million Underwritten Public Offering
Details : The Company currently intends to use the net proceeds to initiate a Phase 1b of CLR 121125 (CLR 125) in triple-negative breast cancer.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
July 02, 2025
Lead Product(s) : CLR 125
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Ladenburg Thalmann & Co
Deal Size : $6.9 million
Deal Type : Public Offering
Lead Product(s) : CLR 125
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Ladenburg Thalmann & Co
Deal Size : $6.0 million
Deal Type : Public Offering
Cellectar Biosciences Announces Pricing of $6 Million Underwritten Public Offering
Details : The Company currently intends to use the net proceeds to initiate a Phase 1b of CLR 121125 (CLR 125) in triple-negative breast cancer.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
July 01, 2025
Lead Product(s) : CLR 125
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Ladenburg Thalmann & Co
Deal Size : $6.0 million
Deal Type : Public Offering
Lead Product(s) : CLR 125
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Nusano
Deal Size : Undisclosed
Deal Type : Agreement
Cellectar Biosciences and U.S.-based Nusano Enter Into Multi-Isotope Supply Agreement
Details : Nusano will provide Cellectar with iodine-125 (I-125) and actinium-225 (Ac-225) for its clinical stage programs, including CLR 125 for triple negative breast cancer and CLR 225 for pancreatic cancer.
Product Name : CLR 121225
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
June 26, 2025
Lead Product(s) : CLR 125
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Nusano
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : CLR 121225
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : NorthStar Medical Radioisotopes
Deal Size : Undisclosed
Deal Type : Agreement
NorthStar Supplies Actinium-225 to Cellectar Biosciences for Therapeutic Use
Details : NorthStar will provide non-carrier added actinium-225 (n.c.a Ac-225) to Cellectar for use in CLR 121225, an actinium-labeled PLE, expected to enter a Phase 1 study in pancreatic cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
November 21, 2024
Lead Product(s) : CLR 121225
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : NorthStar Medical Radioisotopes
Deal Size : Undisclosed
Deal Type : Agreement
Cellectar Fully Exercises Tranche A Warrants, Raising $44.1 Million
Details : Net proceeds will fund CLR 131 (iopofosine I-131), designed for targeted iodine-131 delivery to cancer cells, being evaluated for Waldenstrom Macroglobulinemia and other cancers.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
January 25, 2024
Lead Product(s) : CLR 121225
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Cellectar Broadens Pipeline with Targeted Alpha Therapy for Solid Tumors
Details : CLR 121225 (225Ac-CLR-121225) is an actinium-labeled phospholipid ether. It is a novel α-emitting phospholipid radiotherapeutic conjugate. It is being evaluated for refractory pancreatic cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 16, 2024
Lead Product(s) : CLR 121225
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Cellectar Partners with MiBA to Advance Waldenstrom's Macroglobulinemia Treatment
Details : The partnership aims to advance the treatment of Waldenstrom's macroglobulinemia with Cellectar’s iopofosine I 131, a novel phospholipid radiotherapeutic conjugate.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
January 11, 2024
Cellectar Announces Positive Data Achieving Primary Endpoint in Waldenstrom’s Study
Details : CLR 131 (Iopofosine I 131) is a potential first-in-class, targeted radiotherapy candidate, which is under phase 2 clinical development for relapsed/refractory Waldenstrom’s macroglobulinemia.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
January 08, 2024
Lead Product(s) : CLR131
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : National Cancer Institute
Deal Size : Inapplicable
Deal Type : Inapplicable
Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG
Details : CLR131 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Glioma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 09, 2022
Lead Product(s) : CLR131
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : National Cancer Institute
Deal Size : Inapplicable
Deal Type : Inapplicable