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Collaboration with MSD","therapeuticArea":"Neurology","highestDevelopmentStatus":"Phase I","country":"AUSTRALIA","productType":"Small molecule","productStatus":"New Molecular Entity","date":"September 2023","url1":"","url2":"","graph1":"Neurology","graph2":"Phase I"},{"orgOrder":0,"company":"Bionomics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Bionomics Announces Positive Topline Results from the Phase 2b ATTUNE Clinical Trial of BNC210 in Patients with Post-Traumatic Stress Disorder (PTSD)","therapeuticArea":"Psychiatry\/Psychology","highestDevelopmentStatus":"Phase II","country":"AUSTRALIA","productType":"Small molecule","productStatus":"New Molecular Entity","date":"September 2023","url1":"","url2":"","graph1":"Psychiatry\/Psychology","graph2":"Phase II"},{"orgOrder":0,"company":"Bionomics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not 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Find Clinical Drug Pipeline Developments & Deals by Bionomics
BNC210 is a negative allosteric modulator of the α7 nicotinic acetylcholine receptor, which is being evaluated for the treatment of PTSD and Social Anxiety Disorder.
BNC210 is a negative allosteric modulator of the alpha7 nicotinic acetylcholine receptor under development for the treatment of social anxiety disorder and post-traumatic stress disorder.
BNC210 is a negative allosteric modulator of the alpha7 nicotinic acetylcholine receptor under development for the treatment of SAD and post-traumatic stress disorder.
Under the collaboration, MK-4334, a novel clinical candidate was developed by MSD and derived from Bionomics’ original α7 nAChR PAM candidate (BNC375) for the treatment of cognitive disorders like Alzheimer’s Disease.
BNC210 is a negative allosteric modulator of the alpha7 nicotinic acetylcholine receptor under development for the treatment of SAD and post-traumatic stress disorder.
BNC210 is a negative allosteric modulator of the α7 nicotinic acetylcholine receptor under development for the treatment of SAD and post-traumatic stress disorder.
BNC210 has a novel mechanism of action that involves negative allosteric modulation of the α7 nicotinic acetylcholine receptor. The Company is continuing analysis of the PREVAIL dataset and is assessing next steps for the development of BNC210 in SAD.
BNC210 is an oral, proprietary, selective negative allosteric modulator of the α7 nicotinic acetylcholine receptor, for the acute treatment of Social Anxiety Disorder (“SAD”) and chronic treatment of Post-Traumatic Stress Disorder (PTSD).
The primary objective of Phase 2 PREVAIL Study is to compare each dose level of BNC210 to placebo, and secondary objectives include two other scales measuring participants' anxiety levels. BNC210 is α7 nicotinic acetylcholine receptor modulator used for acute treatment of SAD.
BNC210 is an oral proprietary selective negative allosteric modulator of the α7 nicotinic acetylcholine receptor in development for the acute treatment of SAD and chronic treatment of PTSD. The PREVAIL Study remains on target to initiate by end of 2021.
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