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Find Clinical Drug Pipeline Developments & Deals for APG-1387

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                          01

                          GRx+Biosims
                          Not Confirmed
                          GRx+Biosims
                          Not Confirmed

                          Details : APG-1387 is novel and highly specific small molecule IAP antagonist designed to restore caspase activity and induce apoptosis, as component of combination therapy with immuno-oncology or chemotherapy treatment for solid tumors.

                          Product Name : APG-1387

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 19, 2022

                          Lead Product(s) : APG-1387

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Pharmacy Expo
                          Not Confirmed
                          Pharmacy Expo
                          Not Confirmed

                          Details : Findings from the preclinical study show that APG-1387 is able to clear chronic HBV infection in various mouse models with a unique induction of apoptosis and immunoregulation mechanism.

                          Product Name : APG-1387

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 27, 2020

                          Lead Product(s) : APG-1387,Entecavir

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Pharmacy Expo
                          Not Confirmed
                          Pharmacy Expo
                          Not Confirmed

                          Details : The global multi-center, open-label Phase II study is designed to evaluate the safety and efficacy of APG-1387 in combination with entecavir in patients with CHB who are treatment-naive or -experienced.

                          Product Name : APG-1387

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 17, 2020

                          Lead Product(s) : APG-1387,Entecavir

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharmacy Expo
                          Not Confirmed
                          Pharmacy Expo
                          Not Confirmed

                          Details : The multi-center, open-label clinical trial is comprised of a Phase Ib dose-escalation study and a Phase II efficacy study.

                          Product Name : APG-1387

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 24, 2020

                          Lead Product(s) : APG-1387,Gemcitabine,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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