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CAS 144026-79-9

CAS 144026-79-9

Chemistry, 2 End Use API, 11 Related Intermediates

Manufacturers/Suppliers

2 Suppliers

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Also known as: 144026-79-9, Scandium trifluoromethanesulfonate, Scandium(iii) triflate, Scandium triflate, Sc(otf)3, Mfcd00192433

Molecular Formula

C₃F₉O₉S₃Sc

Molecular Weight

492.2 g/mol

InChI Key

HZXJVDYQRYYYOR-UHFFFAOYSA-K

Slotoxin is a peptide from Centruroides noxius Hoffmann scorpion venom. It belongs to the short scorpion toxin superfamily. Slotoxin reversibly blocks the high conductance calcium-activated potassium channels composed of only -subunits (Kd = 1.5 nM). Unreversibly blocks the high conductance calcium-activated potassium channels composed of - and beta1-subunits. Unreversibly and weakly blocks the high conductance calcium-activated potassium channels composed of - and beta4-subunits. It shows no activity on other potassium channels.

1 2D Structure

CAS 144026-79-9

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

scandium(3+);trifluoromethanesulfonate

2.1.2 InChI

InChI=1S/3CHF3O3S.Sc/c3*2-1(3,4)8(5,6)7;/h3*(H,5,6,7);/q;;;+3/p-3

2.1.3 InChI Key

HZXJVDYQRYYYOR-UHFFFAOYSA-K

2.1.4 Canonical SMILES

C(F)(F)(F)S(=O)(=O)[O-].C(F)(F)(F)S(=O)(=O)[O-].C(F)(F)(F)S(=O)(=O)[O-].[Sc+3]

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Sc(otf)3

2. Scandium Triflate

2.2.2 Depositor-Supplied Synonyms

1. 144026-79-9

2. Scandium Trifluoromethanesulfonate

3. Scandium(iii) Triflate

4. Scandium Triflate

5. Sc(otf)3

6. Mfcd00192433

7. Scandium(3+);trifluoromethanesulfonate

8. Scandium(iii)trifluoromethanesulfonate

9. Trifluoromethanesulfonic Acid Scandium(iii) Salt

10. Scandiumtriflate

11. Scandium(iii) Trifluoromethanesulphonate

12. Scandium (iii) Triflate

13. Scandium(iii) Triflate, 99%

14. Amy9064

15. Dtxsid70370368

16. Scandium Trifluoromethanesulphonate

17. Scandium Trifluoro-methanesulphonate

18. Act08645

19. Bcp16886

20. Akos005063538

21. Scandium(3+) Trifluoromethanesulfonate

22. Scandium(lll) Trifluoromethanesulfonate

23. Gs-6462

24. Sc10825

25. Tris(trifluoromethylsulfonyloxy)scandium

26. S10399

27. Scandium (iii) Trifluoromethanesulfonate

28. Bp-12205

29. Sy003086

30. Ft-0649915

31. Scandium(3+) Ion Tritrifluoromethanesulfonate

32. T1663

33. Scandium(iii)trifluoromethanesulfonateanhydrous

34. Scandium Tris(trifluoromethanesulfonate)

35. A808159

36. Q6364879

37. Scandium(iii) Triflate, 99.995% Trace Metals Basis

38. Scandium(iii) Triflate, Trace Metals Grade 99.995%

39. Scandium(iii) Bis(trifluoromethanesulfonate), Polymer-bound, Macroporous, 30-60 Mesh, Extent Of Labeling: 0.5-1.5 Mmol/g Loading

40. Scandium(iii) Trifluoromethanesulfonate Microencapsulated In A Styrene Polymer [13% Sc(so3cf3)3]

2.3 Create Date

2005-07-19

3 Chemical and Physical Properties

Molecular Formula	C₃F₉O₉S₃Sc
Molecular Weight	492.2 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	18
Rotatable Bond Count	0
Exact Mass	g/mol
Monoisotopic Mass	g/mol
Topological Polar Surface Area	197
Heavy Atom Count	25
Formal Charge	0
Complexity	145
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	4

4 Pharmacology and Biochemistry

4.1 Metabolism/Metabolites

Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases.