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    CAS 334618-23-4
    Also known as: 334618-23-4, (r)-piperidin-3-amine dihydrochloride, (r)-(-)-3-aminopiperidine dihydrochloride, (r)-3-amino-piperidine dihydrochloride, (r)-3-piperidinamine dihydrochloride, (r)-3-aminopiperidine 2hcl
    Molecular Formula
    C5H14Cl2N2
    Molecular Weight
    173.08  g/mol
    InChI Key
    GGPNYXIOFZLNKW-ZJIMSODOSA-N
    1 2D Structure

    CAS 334618-23-4

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (3R)-piperidin-3-amine;dihydrochloride
    2.1.2 InChI
    InChI=1S/C5H12N2.2ClH/c6-5-2-1-3-7-4-5;;/h5,7H,1-4,6H2;2*1H/t5-;;/m1../s1
    2.1.3 InChI Key
    GGPNYXIOFZLNKW-ZJIMSODOSA-N
    2.1.4 Canonical SMILES
    C1CC(CNC1)N.Cl.Cl
    2.1.5 Isomeric SMILES
    C1C[C@H](CNC1)N.Cl.Cl
    2.2 Synonyms
    2.2.1 Depositor-Supplied Synonyms

    1. 334618-23-4

    2. (r)-piperidin-3-amine Dihydrochloride

    3. (r)-(-)-3-aminopiperidine Dihydrochloride

    4. (r)-3-amino-piperidine Dihydrochloride

    5. (r)-3-piperidinamine Dihydrochloride

    6. (r)-3-aminopiperidine 2hcl

    7. (r)-(-)-3-aminopiperidine 2hcl

    8. (3r)-piperidin-3-amine;dihydrochloride

    9. (r)-piperidine-3-amine Dihydrochloride

    10. (3r)-piperidin-3-amine Dihydrochloride

    11. 3-piperidinamine, Dihydrochloride, (3r)-

    12. C5h14cl2n2

    13. Mfcd06799458

    14. R-3-aminopiperidine Dihydrochloride

    15. R-3-aminopiperidine Dihcl

    16. Schembl306090

    17. Dtxsid40583408

    18. 3-amino-piperidine-dihydrochloride

    19. R-3-amino Piperidine Dihcl

    20. Act04891

    21. Cs-b0670

    22. (r)-piperidin-3-aminedihydrochloride

    23. 3-(r)-aminopiperidine Dihydrochloride

    24. Akos015845481

    25. Ac-6185

    26. Ds-0861

    27. Ps-8651

    28. R18a234

    29. (r)-3-amino-piperidine, Dihydrochloride

    30. Db-024517

    31. A5960

    32. Am20090508

    33. (3r)-3-aminopiperidine Dihydrochloride

    34. (r)-piperidin-3-amine Dihydrochloriide

    35. (r)-(-)-3-aminopiperidine Dihydrochloride, 97%

    36. (r)-(-)-3-piperidinamine Dihydrochloride

    37. (3r)-piperidin-3-amine--hydrogen Chloride (1/2)

    38. J-650012

    39. J-650226

    40. W-202369

    41. (r)-(-)-3-aminopiperidine Dihydrochloride, >=98.0% (gc)

    2.3 Create Date
    2007-07-12
    3 Chemical and Physical Properties
    Molecular Weight 173.08 g/mol
    Molecular Formula C5H14Cl2N2
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count0
    Exact Mass172.0534038 g/mol
    Monoisotopic Mass172.0534038 g/mol
    Topological Polar Surface Area38 Ų
    Heavy Atom Count9
    Formal Charge0
    Complexity54
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
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        Tagoor Laboratories, established in 2018, is a part of the Tagoor Group. It specializes in providing APIs...
        Tagoor Laboratories, established in 2018, is a part of the Tagoor Group. It specializes in providing APIs, advanced intermediates and key starting materials for critical and high-growth therapeutic areas, with an emphasis on affordability, quality and timely delivery. It also provides end-to-end CDMO services. Headquartered in Hyderabad, Tagoor Labs is a fast-growing Indian pharma company that serves both branded and generic companies worldwide. The company’s organizational function includes R&D, supply chain, manufacturing, quality testing, quality assurance, regulatory affairs, marketing & sales, and packaging & warehousing departments.
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          Tagoor Laboratories, established in 2018, is a part of the Tagoor Group. It specializes in providing APIs...
          Tagoor Laboratories, established in 2018, is a part of the Tagoor Group. It specializes in providing APIs, advanced intermediates and key starting materials for critical and high-growth therapeutic areas, with an emphasis on affordability, quality and timely delivery. It also provides end-to-end CDMO services. Headquartered in Hyderabad, Tagoor Labs is a fast-growing Indian pharma company that serves both branded and generic companies worldwide. The company’s organizational function includes R&D, supply chain, manufacturing, quality testing, quality assurance, regulatory affairs, marketing & sales, and packaging & warehousing departments.
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            Bulat Pharmaceutical is a fast growing pharmaceutical company, founded in the year 2017, Bulat Pharmaceut...
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              Founded in 2003, Senary Chem is one of the Key High-Tech Enterprises of National Torch Plan. Senary locat...
              Founded in 2003, Senary Chem is one of the Key High-Tech Enterprises of National Torch Plan. Senary located in National Cangzhou Lingang Economic and Technological Development Zone,Cangzhou City,Hebei Province. Senary cover an area of 67,000 square meters, and 300 professionals work there. Senary R&D organization recognized as the Hebei Provincial Engineering Technology Center is comprised of two R & D centers in Tianjin and Cangzhou, and it employs 80 experienced scientists in total. Senary focus on the development, production and sales of advanced pharmaceutical intermediates. Especially, Senary has leading technology and manufacturing capacity for diabetes drug intermediates. All intermediates of DPP4 and SGLT2 class drugs on market have been commercialized production. Senary has 150 sets of 50 ~ 8000L reactor with annual production capacity of 1,000 tons, which can handle both low and high temperature reactions within -100 ~ 240 ℃ range, all kinds of catalytic reactions within 0 ~ 5MPa pressure, and moisture and/or oxygen sensitive reactions. Senary also has expertise in chiral synthesis with leading technologies. The advanced sewage treatment system at Senery has processing capacity of 600 tons daily. Senary has an excellent team that has rich quality management experience.We have established a set of normative and perfect quality managment system,monitoring the whole process of risk assessment,R&D,transfer from pilot scale to commercial production,manufacturing,analysis and sales service. Senary will continue to dedicate on the field of pharmaceutical intermediates to provide the best service for domestic and foreign API pharmaceutical companies with high quality and timely supply of products.
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                Founded in 2003, Senary Chem is one of the Key High-Tech Enterprises of National Torch Plan. Senary locat...
                Founded in 2003, Senary Chem is one of the Key High-Tech Enterprises of National Torch Plan. Senary located in National Cangzhou Lingang Economic and Technological Development Zone,Cangzhou City,Hebei Province. Senary cover an area of 67,000 square meters, and 300 professionals work there. Senary R&D organization recognized as the Hebei Provincial Engineering Technology Center is comprised of two R & D centers in Tianjin and Cangzhou, and it employs 80 experienced scientists in total. Senary focus on the development, production and sales of advanced pharmaceutical intermediates. Especially, Senary has leading technology and manufacturing capacity for diabetes drug intermediates. All intermediates of DPP4 and SGLT2 class drugs on market have been commercialized production. Senary has 150 sets of 50 ~ 8000L reactor with annual production capacity of 1,000 tons, which can handle both low and high temperature reactions within -100 ~ 240 ℃ range, all kinds of catalytic reactions within 0 ~ 5MPa pressure, and moisture and/or oxygen sensitive reactions. Senary also has expertise in chiral synthesis with leading technologies. The advanced sewage treatment system at Senery has processing capacity of 600 tons daily. Senary has an excellent team that has rich quality management experience.We have established a set of normative and perfect quality managment system,monitoring the whole process of risk assessment,R&D,transfer from pilot scale to commercial production,manufacturing,analysis and sales service. Senary will continue to dedicate on the field of pharmaceutical intermediates to provide the best service for domestic and foreign API pharmaceutical companies with high quality and timely supply of products.
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                  Based on the excellent enzymatic technology platform, Enzymaster Chemical applies innovative technology t...
                  Based on the excellent enzymatic technology platform, Enzymaster Chemical applies innovative technology to realize its commercial production of chiral compounds.As a wholly-owned subsidiary of Enzymaster®, we think globally and devote to supply high quality chemical products, which are sustainable supply, with eco-friendly process and competitive price.Meanwhile, we provide domestic and overseas customers biocatalytic custom synthesis serves.
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                    Based on the excellent enzymatic technology platform, Enzymaster Chemical applies innovative technology t...
                    Based on the excellent enzymatic technology platform, Enzymaster Chemical applies innovative technology to realize its commercial production of chiral compounds.As a wholly-owned subsidiary of Enzymaster®, we think globally and devote to supply high quality chemical products, which are sustainable supply, with eco-friendly process and competitive price.Meanwhile, we provide domestic and overseas customers biocatalytic custom synthesis serves.
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                      Alogliptin Benzoate
                      Based on the excellent enzymatic technology platform, Enzymaster Chemical applies innovative technology t...
                      Based on the excellent enzymatic technology platform, Enzymaster Chemical applies innovative technology to realize its commercial production of chiral compounds.As a wholly-owned subsidiary of Enzymaster®, we think globally and devote to supply high quality chemical products, which are sustainable supply, with eco-friendly process and competitive price.Meanwhile, we provide domestic and overseas customers biocatalytic custom synthesis serves.
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                        Jinan Lead Pharmaceutical Technology Co., LTD., located in Jinan, Shandong Province, is mainly engaged in...
                        Jinan Lead Pharmaceutical Technology Co., LTD., located in Jinan, Shandong Province, is mainly engaged in R&D, production and sales of pharmaceutical raw materials and intermediates. The research and development center is located in Jinan high-tech zone, the production base is located in Ulanqab, Inner Mongolia. The plant has 6 production workshops, covering an area of 1,000,000㎡. At present, we have passed the supplier audit from many domestic pharmaceutical enterprises and world-class pharmaceutical enterprises. Main business: pharmaceutical API and intermediate research and development, production and sales.
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                          Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. T...
                          Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. Today we are a leading pharmaceutical bulk drug manufacturer of Intermediates, Advanced Intermediates. Innovation has been forefront of our approach, powered by highly qualified teams and the use of cutting-edge technology. We are a USFDA-approved (USFDA FEI No: 3014053359) company and are continuously expanding our product portfolio and our business to international markets.
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                            Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. T...
                            Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. Today we are a leading pharmaceutical bulk drug manufacturer of Intermediates, Advanced Intermediates. Innovation has been forefront of our approach, powered by highly qualified teams and the use of cutting-edge technology. We are a USFDA-approved (USFDA FEI No: 3014053359) company and are continuously expanding our product portfolio and our business to international markets.
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                              Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. T...
                              Lofty Laboratories was founded in 2005 with a focus on creating an impact in pharmaceutics value chain. Today we are a leading pharmaceutical bulk drug manufacturer of Intermediates, Advanced Intermediates. Innovation has been forefront of our approach, powered by highly qualified teams and the use of cutting-edge technology. We are a USFDA-approved (USFDA FEI No: 3014053359) company and are continuously expanding our product portfolio and our business to international markets.
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                              Mehta API Pvt Ltd engaged in manufacturing and marketing of APIs & Advance Drug Intermediates.... Globall...
                              Mehta API Pvt Ltd engaged in manufacturing and marketing of APIs & Advance Drug Intermediates.... Globally. Mehta Api has been inordinately proud of its achievements since its inception .Our journey is paved with many success stories. Much of it has, in many ways, been unprecedented in the Pharma industry. Our success has been validated by what we hold the dearest - Product Excellence and Customer service. We believe that long-term business success is rooted in value. Business ethics are good business; they are like a long-term insurance policy. We are committed to Excellence in Product Quality and adherence to stringent delivery schedule.
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                                Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and ...
                                Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and technical service of APIs, pharmaceutical intermediates and specialty chemicals. The marketing department is located in Nanjing. We have two GMP facilities in Jiangsu Province and cooperative factories in Zhejiang Province. The leading products range of the company is oncology and anti-diabetes . We also specialize in custom synthesis and contract research which demonstrates our state-of-the-art technology and capacity of synthesis.
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                                  Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and ...
                                  Nanjing Lift Pharmaceutical is a specialized company concentrating on the R&D, production, marketing and technical service of APIs, pharmaceutical intermediates and specialty chemicals. The marketing department is located in Nanjing. We have two GMP facilities in Jiangsu Province and cooperative factories in Zhejiang Province. The leading products range of the company is oncology and anti-diabetes . We also specialize in custom synthesis and contract research which demonstrates our state-of-the-art technology and capacity of synthesis.
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                                  (R)-3 aminopiperidine Di hydrochloride

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                                  VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                  VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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