Rochem International Inc Rochem International Inc

X

CAS 145546-80-1 manufacturers and suppliers on PharmaCompass

PharmaCompass
CAS 145546-80-1
Also known as: 120014-07-5, 145546-80-1, 1-benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine, (e)-2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1h-inden-1-one, Donepezil related compound a, (2e)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-3h-inden-1-one
Molecular Formula
C24H27NO3
Molecular Weight
377.5  g/mol
InChI Key
LPMOTUSFDTTWJL-UDWIEESQSA-N
FDA UNII
1D3K90DIY3

1 2D Structure

CAS 145546-80-1

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-3H-inden-1-one
2.1.2 InChI
InChI=1S/C24H27NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,12,14-15,17H,8-11,13,16H2,1-2H3/b20-12+
2.1.3 InChI Key
LPMOTUSFDTTWJL-UDWIEESQSA-N
2.1.4 Canonical SMILES
COC1=C(C=C2C(=C1)CC(=CC3CCN(CC3)CC4=CC=CC=C4)C2=O)OC
2.1.5 Isomeric SMILES
COC1=C(C=C2C(=C1)C/C(=C\C3CCN(CC3)CC4=CC=CC=C4)/C2=O)OC
2.2 Other Identifiers
2.2.1 UNII
1D3K90DIY3
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 120014-07-5

2. 145546-80-1

3. 1-benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine

4. (e)-2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1h-inden-1-one

5. Donepezil Related Compound A

6. (2e)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-3h-inden-1-one

7. 1d3k90diy3

8. Chembl168938

9. (2e)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-2,3-dihydro-1h-inden-1-one

10. (2e)-dehydrodonepezil

11. (e)-2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxyindan-1-one

12. 1h-inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-, (2e)-

13. 2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxyindan-1-one, (e)-

14. 2-[1-(1-benzyl-piperidin-4-yl)-meth-(e)-ylidene]-5,6-dimethoxy-indan-1-one

15. (2~{e})-5,6-dimethoxy-2-[[1-(phenylmethyl)piperidin-4-yl]methylidene]-3~{h}-inden-1-one

16. 1h-inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methylene)-, (2e)-

17. (e)-2-[(1-benzylpiperidin-4-yl)methylene]-5,6-dimethoxyindan-1-one

18. Donepezil Impurity 14

19. Unii-1d3k90diy3

20. 1-benzyl-4-((5,6-dimethoxy-1-oxoindan-2-ylidene)methyl)piperidine

21. 2-[(1-benzylpiperidin-4-yl)methylene]-2,3-dihydro-5,6-dimethoxyinden-1-one

22. Zinc597028

23. Bcp28366

24. Vfa54680

25. Bdbm50280646

26. Mfcd08693144

27. Donepezil Related Compound A- [usp]

28. Akos000277341

29. Cs-w006058

30. Dehydro Donepezil (donepezil Impurity)

31. Ds-0813

32. 1h-inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-

33. Ac-26327

34. Cs-0166756

35. Donepezil Related Compound A [usp-rs]

36. 014b075

37. Donepezil Related Compound A [usp Impurity]

38. Q27252264

39. Donepezil Hydrochloride Impurity F [ep Impurity]

40. 2-[(1-benzyl-4-piperidyl)methylene]-5,6-dimethoxy-1-indanone

41. (e)-2-(1-benzyl-4-piperidylmethylene)-5,6-dimethoxy-1-indanone

42. 1-benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)-piperidine

43. 2-[(1-benzylpiperidine-4-yl)methylene]-5,6-dimethoxyindan-1-one

44. 1h-inden-1-one,2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-

45. 2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydroinden-1-one

46. (e)-2-[(1-benzylpiperidin-4-yl)methylene]-5,6-dimethoxyindan-1-one(donepezil Related Compound A)

47. Dz7

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 377.5 g/mol
Molecular Formula C24H27NO3
XLogP34.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass377.19909372 g/mol
Monoisotopic Mass377.19909372 g/mol
Topological Polar Surface Area38.8 Ų
Heavy Atom Count28
Formal Charge0
Complexity560
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
Flag China
Digital Content Digital Content
URL Supplier Web Content
120014-07-5
Founded in 2003, Senary Chem is one of the Key High-Tech Enterprises of National Torch Plan. Senary locat...
Founded in 2003, Senary Chem is one of the Key High-Tech Enterprises of National Torch Plan. Senary located in National Cangzhou Lingang Economic and Technological Development Zone,Cangzhou City,Hebei Province. Senary cover an area of 67,000 square meters, and 300 professionals work there. Senary R&D organization recognized as the Hebei Provincial Engineering Technology Center is comprised of two R & D centers in Tianjin and Cangzhou, and it employs 80 experienced scientists in total. Senary focus on the development, production and sales of advanced pharmaceutical intermediates. Especially, Senary has leading technology and manufacturing capacity for diabetes drug intermediates. All intermediates of DPP4 and SGLT2 class drugs on market have been commercialized production. Senary has 150 sets of 50 ~ 8000L reactor with annual production capacity of 1,000 tons, which can handle both low and high temperature reactions within -100 ~ 240 ℃ range, all kinds of catalytic reactions within 0 ~ 5MPa pressure, and moisture and/or oxygen sensitive reactions. Senary also has expertise in chiral synthesis with leading technologies. The advanced sewage treatment system at Senery has processing capacity of 600 tons daily. Senary has an excellent team that has rich quality management experience.We have established a set of normative and perfect quality managment system,monitoring the whole process of risk assessment,R&D,transfer from pilot scale to commercial production,manufacturing,analysis and sales service. Senary will continue to dedicate on the field of pharmaceutical intermediates to provide the best service for domestic and foreign API pharmaceutical companies with high quality and timely supply of products.
ASK
US
PHARMACOMPASS
Upload
your Marketing & Sales content
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty
Post Enquiry
POST ENQUIRY