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Fuji Yakuhin
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Japan
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4-383 Sakuragicho, Omiya-ku, Saitama-shi
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048-644-3240
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Urece (dotinurad) is a potential best-in-class urate transporter inhibitor that is currently in Phase 1 clinical trial and being developed for the treatment of gout. It can lower blood uric acid levels by selectively inhibiting URAT1 and uric acid reabsorption in the kidneys.


Lead Product(s): Dotinurad

Therapeutic Area: Rheumatology Product Name: Urece

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Urica Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement December 14, 2022

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Dotinurad (URECE® tablet) was approved in Japan in 2020 as a once-daily oral therapy for gout and hyperuricemia. Dotinurad was efficacious and well-tolerated in more than 500 Japanese patients treated for up to 58 weeks in Phase 3 clinical trials.


Lead Product(s): Dotinurad

Therapeutic Area: Rheumatology Product Name: Urece

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Fortress Biotech

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 31, 2022

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Dotinurad is a potential best-in-class urate transporter (URAT1) inhibitor that was approved for the treatment of gout and hyperuricemia in Japan in 2020.


Lead Product(s): Dotinurad

Therapeutic Area: Musculoskeletal Product Name: Undisclosed

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Fortress Biotech

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement May 10, 2021

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Under this agreement, Eisai will proceed with the development of dotinurad in China.


Lead Product(s): Dotinurad

Therapeutic Area: Rheumatology Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Eisai

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement February 25, 2020

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