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Jynneos (live nonreplicating smallpox and monkeypox vaccine) is approved for prevention of smallpox and monkeypox disease in adults 18 years of age and older determined to be at high risk for smallpox or monkeypox infection.


Lead Product(s): Live Nonreplicating Smallpox and Monkeypox Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: Jynneos

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 02, 2024

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Jynneos (live nonreplicating smallpox and monkeypox vaccine) is approved for prevention of smallpox and monkeypox disease in adults 18 years of age and older determined to be at high risk for smallpox or monkeypox infection.


Lead Product(s): Live Nonreplicating Smallpox and Monkeypox Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: Jynneos

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 13, 2024

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PXVX0317 (CHIKV VLP) vaccine is comprised of chikungunya virus-like particles (CHIKV VLP), adsorbed on aluminum hydroxide (Alhydrogel®) adjuvant 2%. It is being evaluated for the treatment of chikungunya fever.


Lead Product(s): CHIKV VLP

Therapeutic Area: Infections and Infectious Diseases Product Name: PXVX0317

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 23, 2024

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JYNNEOS® (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) is approved for the prevention of smallpox and mpox disease in adults 18 years of age and older determined to be at high risk for smallpox and mpox infection.


Lead Product(s): Live Nonreplicating Smallpox and Monkeypox Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: Jynneos

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 25, 2023

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Under the agreement, Bavarian will supply its Imvanex (MVA-BN or modified vaccinia ankara ) non-replicating smallpox vaccine to rescEU, a strategic reserve within the European Union.


Lead Product(s): Modified Vaccinia Ankara

Therapeutic Area: Infections and Infectious Diseases Product Name: Imvanex

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: European Union

Deal Size: $11.8 million Upfront Cash: Undisclosed

Deal Type: Agreement September 13, 2023

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ABNCoV2 is being developed as a universal booster to any other type of COVID-19 vaccine and has shown potential to boost neutralizing antibodies against SARS-CoV-2, including variants of concern, to levels associated with a high degree of protection.


Lead Product(s): ABNCoV2

Therapeutic Area: Infections and Infectious Diseases Product Name: ABNCoV2

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 31, 2023

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PXVX0317 (CHIKV VLP) vaccine candidate was well tolerated and induced a robust and durable serum neutralizing antibody immune response against the Chikungunya virus up to two years.


Lead Product(s): CHIKV VLP

Therapeutic Area: Infections and Infectious Diseases Product Name: PXVX0317

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 06, 2023

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MVA-BN RSV is based on bavarian nordic’s proprietary vaccine platform technology, MVA-BN, and incorporates five distinct RSV antigens to stimulate a broad immune response against both RSV subtypes (A and B).


Lead Product(s): MVA-BN-RSV Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: MVA-BN-RSV

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 22, 2023

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Details:

ABNCoV2 is being developed as a universal booster to any other type of COVID-19 vaccine and has shown potential to boost neutralizing antibodies against SARS-CoV-2, including variants of concern, to levels associated with a high degree of protection.


Lead Product(s): ABNCoV2

Therapeutic Area: Infections and Infectious Diseases Product Name: ABNCoV2

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 27, 2023

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Details:

PXVX0317 (CHIKV VLP) vaccine candidate was well tolerated and induced a robust and durable serum neutralizing antibody immune response against the Chikungunya virus up to two years.


Lead Product(s): CHIKV VLP

Therapeutic Area: Infections and Infectious Diseases Product Name: PXVX0317

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 20, 2023

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