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Huadong Medicine
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China
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No.866, Mogan Mountain Road, Hangzhou
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+86-571-89903388
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Under the collaboration, Huadong will receive license for both the cream and foam formulations of topical Zoryve (roflumilast), a next generation PDE4 inhibitor, for multiple dermatological conditions including plaque psoriasis, seborrheic dermatitis, and atopic dermatitis.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Arcutis Biotherapeutics

Deal Size: $94.2 million Upfront Cash: $30.0 million

Deal Type: Collaboration August 10, 2023

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Under the terms of the exclusive licensing agreement, Huadong will advance research and development costs for Ashvattha’s hydroxyl dendrimer clinical candidates, OP-101, D-4517.2 and OP-801, and for additional preclinical candidates.


Lead Product(s): Dendrimer N-acetyl-cysteine

Therapeutic Area: Infections and Infectious Diseases Product Name: OP-101

Highest Development Status: Phase IIProduct Type: Large molecule

Recipient: Ashvattha Therapeutics

Deal Size: $45.0 million Upfront Cash: Undisclosed

Deal Type: Licensing Agreement April 27, 2022

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CT053 (zevorcabtagene autoleucel), is a fully human, autologous BCMA CAR T-cell product candidate for the treatment of relapsed/refractory multiple myeloma (R/R MM).


Lead Product(s): Zevorcabtagene Autoleucel

Therapeutic Area: Oncology Product Name: CT053

Highest Development Status: Phase I/ Phase IIProduct Type: Cell and Gene therapy

Recipient: CARsgen Therapeutics

Deal Size: $181.3 million Upfront Cash: $29.6 million

Deal Type: Collaboration January 16, 2022

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