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Xyphos Biosciences
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Under the term of the license agreement, the companies plan to combine Kelonia's iGPS with Xyphos' ACCEL technology to develop innovative in vivo CAR-T Cell therapies for Immuno-oncology.


Lead Product(s): CAR-T Cell Therapy

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Cell and Gene therapy

Recipient: Kelonia Therapeutics

Deal Size: $840.0 million Upfront Cash: $40.0 million

Deal Type: Licensing Agreement February 15, 2024

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The companies will jointly conduct research activities to identify and optimize proprietary LENS Integrated Intelligence Technology in silico generated antibodies, targeting an undisclosed target in the TME, as potential therapeutic development candidates.


Lead Product(s): Antibody

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Recipient: Talem Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration March 30, 2023

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The collaboration will leverage Phanes’ proprietary technology platforms, PACbody and SPECpair, in the evaluation of cell therapies in oncology. The company has its proprietary technology platforms to develop novel biologics that address high unmet medical needs in cancer.


Lead Product(s): Bispecific Antibody

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Recipient: Phanes Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration March 06, 2023

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GO will lead the collaboration to discover high-affinity antibodies against the two targets, and Astellas will be responsible for research activities, clinical development and commercialization of the therapeutics derived from the antibodies for Immuno-Oncology.


Lead Product(s): Antibody

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Recipient: GO Therapeutics

Deal Size: $783.5 million Upfront Cash: $20.5 million

Deal Type: Collaboration June 01, 2022

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The agreement covers VIVEbiotech long-term supplying lentiviral vectors for Xyphos’ upcoming clinical trial of its lead convertibleCAR-T™ program. This involves VIVEbiotech manufacturing lentiviral vectors for both preclinical and clinical phases.


Lead Product(s): Lentiviral vectors,convertible CAR-T cells

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Cell and Gene therapy

Recipient: VIVEbiotech

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration June 04, 2020

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