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XTMAB-16, an anti-TNFα monoclonal antibody which is being tested in a Phase 1b/2a clinical trial for its ability to potentially help patients with pulmonary sarcoidosis, a chronic, multisystem inflammatory disorder.


Lead Product(s): XTMAB-16

Therapeutic Area: Immunology Product Name: XTMAB-16

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 15, 2023

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Under the agreement, Meitheal gains exclusive rights to commercialize XTMAB-16, a monoclonal antibody which aims to treat people with sarcoidosis, in North America and Xentria remains responsible for clinical development and retains the marketing rights in all other countries.


Lead Product(s): XTMAB-16

Therapeutic Area: Immunology Product Name: XTMAB-16

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Meitheal Pharmaceuticals

Deal Size: $680.0 million Upfront Cash: $45.0 million

Deal Type: Licensing Agreement June 27, 2023

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XTMAB16, an Investigational new drug candidate, is a chimeric human-murine IgG1 anti-TNF monoclonal antibody being developed as a novel biologic product for treatment of sarcoidosis also, suppress the physiologic response to tumor necrosis factor.


Lead Product(s): XTMAB-16

Therapeutic Area: Rare Diseases and Disorders Product Name: XTMAB-16

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 08, 2022

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