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Details:
T-Guard (ricin toxin A conjugated mAB) is designed to reset the body's immune system in life-threatening T cell‒mediated conditions, potentially including prevention of transplant-related rejection, treatment of acute solid-organ rejection, and severe autoimmune disease.
Lead Product(s): Ricin Toxin A Conjugated Monoclonal Antibodies
Therapeutic Area: Immunology Product Name: T-Guard
Highest Development Status: Phase IIIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Xenikos B.V
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 28, 2022
Details:
VEL-101/FR104 is a novel investigational maintenance immunosuppressive agent being developed for prevention of acute rejection in kidney transplant recipients.
Lead Product(s): FR104
Therapeutic Area: Immunology Product Name: VEL-101
Highest Development Status: Phase IProduct Type: Large molecule
Partner/Sponsor/Collaborator: OSE Immunotherapeutics SA
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 18, 2022
Details:
VEL-101 (FR104) is a novel investigational maintenance immunosuppressive agent being developed for prevention of acute rejection in kidney transplant recipients.
Lead Product(s): VEL-101
Therapeutic Area: Immunology Product Name: FR104
Highest Development Status: Phase IProduct Type: Large molecule
Partner/Sponsor/Collaborator: Asahi Kasei Pharma
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 18, 2022
Details:
The collaboration grants Veloxis worldwide rights to develop, manufacture and commercialize FR104, a CD28 antagonist monoclonal antibody fragment, for all transplant indications. OSE Immunotherapeutics retains all rights to develop FR104 in autoimmune diseases.
Lead Product(s): FR104
Therapeutic Area: Immunology Product Name: FR104
Highest Development Status: Phase IProduct Type: Large molecule
Recipient: OSE Immunotherapeutics SA
Deal Size: $393.6 million Upfront Cash: $8.5 million
Deal Type: Collaboration April 26, 2021