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Veloxis Pharmaceuticals
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U.S.A
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1001 Winstead Drive, Cary, NC 27513
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1 919 591 3090
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T-Guard (ricin toxin A conjugated mAB) is designed to reset the body's immune system in life-threatening T cell‒mediated conditions, potentially including prevention of transplant-related rejection, treatment of acute solid-organ rejection, and severe autoimmune disease.


Lead Product(s): Ricin Toxin A Conjugated Monoclonal Antibodies

Therapeutic Area: Immunology Product Name: T-Guard

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Xenikos B.V

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 28, 2022

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VEL-101/FR104 is a novel investigational maintenance immunosuppressive agent being developed for prevention of acute rejection in kidney transplant recipients.


Lead Product(s): FR104

Therapeutic Area: Immunology Product Name: VEL-101

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: OSE Immunotherapeutics SA

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 18, 2022

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VEL-101 (FR104) is a novel investigational maintenance immunosuppressive agent being developed for prevention of acute rejection in kidney transplant recipients.


Lead Product(s): VEL-101

Therapeutic Area: Immunology Product Name: FR104

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Asahi Kasei Pharma

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 18, 2022

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The collaboration grants Veloxis worldwide rights to develop, manufacture and commercialize FR104, a CD28 antagonist monoclonal antibody fragment, for all transplant indications. OSE Immunotherapeutics retains all rights to develop FR104 in autoimmune diseases.


Lead Product(s): FR104

Therapeutic Area: Immunology Product Name: FR104

Highest Development Status: Phase IProduct Type: Large molecule

Recipient: OSE Immunotherapeutics SA

Deal Size: $393.6 million Upfront Cash: $8.5 million

Deal Type: Collaboration April 26, 2021

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