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Pivya (pivmecillinam) oral tablets have been approved by the FDA for treating uncomplicated urinary tract infections (UTIs) in adult females caused by susceptible isolates of Escherichia coli, Proteus mirabilis, and Staphylococcus saprophyticus.


Lead Product(s): Pivmecillinam

Therapeutic Area: Infections and Infectious Diseases Product Name: Pivya

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 24, 2024

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The net proceeds will be used for the development and commercialization of two European-approved antibiotics, including Pivya (pivmecillinam), an oral prodrug of mecillinam, and mecillinam, an intravenous (IV) formulation, for the treatment of urinary tract infections.


Lead Product(s): Pivmecillinam

Therapeutic Area: Infections and Infectious Diseases Product Name: Pivya

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: AMR Action Fund

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Financing January 17, 2024

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Pivmecillinam is an oral prodrug of mecillinam that is being developed for uncomplicated UTI (uUTI), and it has a unique mechanism of action for infections caused by Gram-negative bacteria, including extended spectrum beta-lactamases.


Lead Product(s): Pivmecillinam

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 29, 2021

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Details:

Pivmecillinam is an oral prodrug of mecillinam that is being developed for uncomplicated UTI (uUTI), and it has a unique mechanism of action for infections caused by Gram-negative bacteria, including extended-spectrum beta-lactamases.


Lead Product(s): Pivmecillinam

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 15, 2021

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