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twoXAR Pharmaceutical
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Country
U.S.A
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883 N. Shoreline Blvd, Suite A100, Mountain View, CA 940
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(650) 382-2605

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TXR-1208 and TXR-1210 represent two different novel mechanisms of action (MOA). The overall timing to complete predictions, select hits and begin in vivo testing was a total of four weeks, significantly faster than traditional drug discovery processes.


Lead Product(s): TXR-1208

Therapeutic Area: Nephrology Product Name: TXR-1208

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 04, 2021

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In vivo efficacy with TXR-611 and 612 was evaluated using STAM™ mouse model where hits showed good tolerability and significant decrease in liver weight, steatosis, ballooning, fibrillar collagen deposition, NAFLD activity score and efficacy compares favorably to telmisartan.


Lead Product(s): TXR-611

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: TXR-611

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 13, 2020

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TXR-311 was identified, screened and selected as an in vivo candidate and demonstrated efficacy comparable to sorafenib with good tolerability.


Lead Product(s): TXR-311

Therapeutic Area: Oncology Product Name: TXR-311

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 22, 2020

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TXR-711 and TXR-712, demonstrated significant efficacy and excellent tolerability in preclinical studies.


Lead Product(s): TXR-711

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Undisclosed

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 21, 2020

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