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SynOx Therapeutics
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Wilton Terrace, 7/8, Dublin City, County Dublin D02 KC57, IE
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The proceeds will be used to advance late-stage product Emactuzumab, SynOx's potentially best-in-class CSF-1(R) inhibiting monoclonal antibody for the treatment of Tenosynovial Giant Cell Tumour.


Lead Product(s): Emactuzumab

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Forbion

Deal Size: $75.0 million Upfront Cash: Undisclosed

Deal Type: Series B Financing April 22, 2024

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Emactuzumab is a novel monoclonal antibody inhibiting CSF-1R that offers a short course of treatment. Phase I/II studies indicated good tolerability and a manageable safety profile and substantial preliminary efficacy in TGCT patients.


Lead Product(s): Emactuzumab

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 31, 2022

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The financing will enable SynOx to continue the development of emactuzumab, for the treatment of diffuse tenosynovial giant cell tumours (“TGCT”), also known as pigmented villonodular synovitis (”PVNS”), and other indications.


Lead Product(s): Emactuzumab

Therapeutic Area: Oncology Product Name: CXD301

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Healthcaps India

Deal Size: $45.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing November 19, 2020

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