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Statera Biopharma
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Details:

The agreement allows Statera the right to supply the IgY products for the existing approved markets. Statera also receives the right to license and commercialize current and future products for other indications.


Lead Product(s): Avian Antibody

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Large molecule

Recipient: Lay Sciences

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership May 13, 2022

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Statera will receive milestones, new indications and royalties, Crohn’s disease and COVID-19 indications and regulatory approvals, payments from Immune Therapeutics in exchange for Statera’s rights to any product containing low-dose naltrexone as an active ingredient.


Lead Product(s): Naltrexone Hydrochloride

Therapeutic Area: Infections and Infectious Diseases Product Name: STAT-205

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Immune Therapeutics

Deal Size: $402.0 million Upfront Cash: $2.0 million

Deal Type: Agreement April 27, 2022

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Under the terms of the definitive agreement, Statera will receive upfront payment and revenue-based milestone payments from Coeptis in exchange for Statera’s rights to any product containing Entolimod as an active ingredient and all other related TLR5 agonists.


Lead Product(s): Entolimod

Therapeutic Area: Oncology Product Name: CBLB502

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Coeptis Therapeutics

Deal Size: Undisclosed Upfront Cash: $6.0 million

Deal Type: Agreement April 13, 2022

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STAT-205 may show promise in treating both acute COVID infections and long COVID in this manner. Preliminary in vitro data demonstrated the drug’s ability to slow or halt the progression of SARS-CoV-2 (the virus that causes COVID-19) in human lung cells.


Lead Product(s): Naltrexone Hydrochloride

Therapeutic Area: Infections and Infectious Diseases Product Name: STAT-205

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 02, 2022

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This financing will be used for general corporate purposes, including the Company’s Phase 3 pediatric Crohn’s study for STAT-201, its acute COVID study, as well as other development activities.


Lead Product(s): STAT-201

Therapeutic Area: Gastroenterology Product Name: STAT-201

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: EF Hutton

Deal Size: $2.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering February 09, 2022

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STAT-201, Statera’s most advanced drug candidate, in Phase 2 study demonstrated proof of concept and safety as well as remission in 67% of participants and 43% of true mucosal healing with endoscopies.


Lead Product(s): STAT-201

Therapeutic Area: Gastroenterology Product Name: STAT-201

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 29, 2021

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Statera is establishing a development program in Oncology and Hematology based on the potential that toll-like receptor 5 agonists, such as Entolimod, have shown in the treatment of neutropenia and anemia in cancer patients.


Lead Product(s): Entolimod

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: STAT-600

Highest Development Status: UndisclosedProduct Type: Peptide

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 01, 2021

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During preclinical in vitro studies, STAT-205 demonstrated an ability to inhibit the replication of coronaviruses in human lung cells. Data also shows that STAT-205 could prevent life-threatening lung inflammation caused by COVID-19, as well as lessen the risk of reinfection.


Lead Product(s): STAT-205

Therapeutic Area: Infections and Infectious Diseases Product Name: STAT-205

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 19, 2021

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