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SpyBiotech
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United Kingdom
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SpyBiotech Limited 7600 Quorum Oxford Business Park North Oxford OX4 2JZ United Kingdom
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+44 (0)1865 582088
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SpyBiotech's primary program, SPYVLP01, a candidate vaccine, is presently undergoing Phase I clinical trial evaluation with patients for the treatment of human cytomegalovirus infection.


Lead Product(s): SPYVLP01

Therapeutic Area: Infections and Infectious Diseases Product Name: SPYVLP01

Highest Development Status: Phase IProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 07, 2023

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SPYVLP01, a vaccine targeting human cytomegalovirus (HCMV) using its Hepatitis B virus-like-particle platform technology. There is currently no approved vaccine against HCMV.


Lead Product(s): SPYVLP01

Therapeutic Area: Infections and Infectious Diseases Product Name: SPYVLP01

Highest Development Status: IND EnablingProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 20, 2023

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The funding will support the development of next generation pan-SARS-CoV-2 and pan-sarbecovirus vaccines using novel SpyVector platform. SpyVector is a platform based on recombinant adenovirus.


Lead Product(s): Undisclosed

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Vaccine

Partner/Sponsor/Collaborator: Bill & Melinda Gates Foundation

Deal Size: $4.0 million Upfront Cash: Undisclosed

Deal Type: Funding March 20, 2023

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Proceeds will advance the clinical development of SpyBiotech’s novel vaccine technology platform, based on its proprietary SpyCatcher/SpyTag protein “superglue” technology.


Lead Product(s): Undisclosed

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Vaccine

Partner/Sponsor/Collaborator: Braavos Investment Advisers

Deal Size: $32.5 million Upfront Cash: Undisclosed

Deal Type: Series A Financing February 10, 2021

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SpyBiotech selected 3P Biopharmaceuticals in June 2019 to manufacture a cGMP batch of their virus-like-particle carrier with the goal of completing production in 2021. This carrier will be used to display antigens from different pathogens.


Lead Product(s): VLPs based vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Vaccine

Recipient: 3P Biopharmaceuticals

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement October 27, 2020

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SpyBiotech has signed an exclusive global licensing agreement with SIIPL for the development of a novel virus-like-particle (VLP) vaccine targeting COVID-19. The Phase I/II study has been initiated in Australia.


Lead Product(s): Virus-like-particle vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: Phase I/ Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Serum Institute of India

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement September 08, 2020

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